Mild and efficient hydrolysis of thioglycosides to glycosyl hemiacetals using N-iodosaccharin

被引：12

作者：

Mandal, Pintu Kumar ^{[1
]}

Misra, Anup Kumar ^{[1
]}

机构：

[1] Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226001, Uttar Pradesh, India

来源：

SYNLETT | 2007年 / 08期

关键词：

carbohydrate; hydrolysis; thioglycoside; hemiacetals; N-iodosaccharin;

D O I：

10.1055/s-2007-977412

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient methodology has been developed for the mild hydrolysis of thioglycosides to the corresponding hemiacetals using N-iodosaccharin without any requirement of co-activator. Most of the functional groups used for the protecting group manipulation of carbohydrates remain unaffected under the reaction conditions.

引用

页码：1207 / 1210

页数：4

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