Separation selectivity in chiral and achiral capillary electrophoresis with mixed cyclodextrins

被引:93
作者
Lurie, IS [1 ]
机构
[1] US Drug Enforcement Adm, Special Testing & Res Lab, Mclean, VA 22102 USA
关键词
buffer composition; enantiomer separation; reviews; selectivity; cyclodextrins;
D O I
10.1016/S0021-9673(97)00700-0
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The use of mixed cyclodextrins (CDs) as run buffer additives for capillary electrophoresis (CE) is reviewed. Mixtures of neutral CDs or neutral and charged CDs are advantageous for both chiral and achiral separations. The unique selectivities offered by these novel combinations allow separations that are often problematic to obtain by other CE techniques. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:297 / 307
页数:11
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