Systemic lupus erythematosus and hypertension

被引：59

作者：

Munguia-Realpozo, Pamela ^{[1
,2
]}

Mendoza-Pinto, Claudia ^{[1
,2
,3
]}

Sierra Benito, Cristina ^{[4
]}

Escarcega, Ricardo O. ^{[5
]}

Garcia-Carrasco, Mario ^{[1
,2
,3
]}

Mendez Martinez, Socorro ^{[6
]}

Etchegaray Morales, Ivet ^{[2
]}

Galvez Romero, Jose Luis ^{[7
]}

Ruiz-Arguelles, Alejandro ^{[8
]}

Cervera, Ricard ^{[9
]}

机构：

[1] UMAE, Hosp Especialidades, Syst Autoimmune Dis Res Unit, Inst Mexican Seguro Social, Puebla, Puebla, Mexico

[2] Benemerita Univ Autnoma Puebla, Med Sch, Immunol & Rheumatol, Puebla, Mexico

[3] IMSS, Ctr Invest Biomed Oriente, Puebla, Puebla, Mexico

[4] Univ Barcelona, IDIBAPS, Hosp Clin Barcelona, Internal Med Dept,Hypertens & Vasc Risk Unit, Barcelona, Spain

[5] Florida Heart Associates Heart & Vasc Inst, Ft Myers, FL USA

[6] Inst Mexican Seguro Social, Res Hlth Coordinat, Puebla, Puebla, Mexico

[7] Jefatura Invest ISSSTE, Puebla, Mexico

[8] Lab Clin Puebla, Puebla, Mexico

[9] Hosp Clin Barcelona, Dept Autoinunune Dis, Barcelona, Spain

来源：

AUTOIMMUNITY REVIEWS | 2019年 / 18卷 / 10期

关键词：

Systemic lupus erythematosus; Hypertension; Cardiovascular disease; Guidelines; ATHEROSCLEROTIC VASCULAR EVENTS; CORONARY-HEART-DISEASE; BLOOD-PRESSURE; RISK-FACTORS; CARDIOVASCULAR-DISEASE; SUBCLINICAL ATHEROSCLEROSIS; RHEUMATOID-ARTHRITIS; PREMATURE ATHEROSCLEROSIS; ENDOTHELIAL DYSFUNCTION; METABOLIC SYNDROME;

D O I：

10.1016/j.autrev.2019.102371

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Systemic lupus erythematosus (SLE) is associated with a high burden of cardiovascular disease (CVD), which is in part imputed to classical vascular risk factors such as hypertension. Hypertension is frequent among patients with SLE and studies show it is more prevalent in SLE patients than in people without SLE. Despite the high frequency of hypertension in SLE patients, the pathophysiological mechanisms underlying the development of hypertension remain poorly understood. 24-h ambulatory blood pressure monitoring has emerged as a valuable tool in determining blood pressure (BP) in SLE patients in whom hypertension has been associated with damage accrual, stroke and cognitive dysfunction. Although prevalent, current guidelines neglect the specific management of hypertension in SLE patients in their recommendations. This review discusses the mechanisms that may lead to hypertension and the literature evaluating hypertension screening and management in SLE patients.

引用

页数：8

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