Synthesis of benzylcyanoborane adducts of amines and separation of their enantiomers;: SN2 substitution at boron atom

被引：25

作者：

Charoy, L

Valleix, A

Toupet, L

Le Gall, T

van Chuong, PP

Mioskowski, C

机构：

[1] CEA Saclay, Serv Mol Marquees, Dept Biol Cellulaire & Mol, F-91191 Gif Sur Yvette, France

[2] Univ Rennes 1, Grp Mat Condense & Mat, UMR 6626, F-35042 Rennes, France

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 22期

关键词：

D O I：

10.1039/b006265k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Benzylcyanoborane adducts of several amines were prepared in four steps from toluene, their enantiomers were separated using chiral phase HPLC and an S(N)2 pathway was evidenced in the reaction of a trimethylamine-derived enantiomer with pyridine.

引用

页码：2275 / 2276

页数：2

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