Dopamine D2 receptor TaqIA and TaqIB polymorphisms in Parkinson's disease

被引：29

作者：

Tan, EK

Tan, Y

Chai, A

Tan, C

Shen, H

Lum, SY

Fook-Cheong, SMC

Teoh, ML

Yih, Y

Wong, MC

Zhao, Y

机构：

[1] Singapore Gen Hosp, Dept Neurol, Singapore 169608, Singapore

[2] Singapore Gen Hosp, Dept Clin Res, Singapore 169608, Singapore

[3] Singapore Gen Hosp, Dept Hlth Screening, Singapore 169608, Singapore

[4] Natl Inst Neurosci, Singapore, Singapore

来源：

MOVEMENT DISORDERS | 2003年 / 18卷 / 05期

关键词：

dopamine receptor D2; polymorphism; smoking; Parkinson's disease;

D O I：

10.1002/mds.10406

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In a case control study, we examined the association of DRD2 Taq1A and Taq1B polymorphisms and risk of PD, and evaluated the strength of linkage disequilibrium of the polymorphisms. The Taq1A and Taq1B polymorphisms were in strong linkage disequilibrium. There was, however, no significant association of the two polymorphisms with PD. (C) 2003 Movement Disorder Society.

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收藏

页码：593 / 595

页数：3

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