Pd-Catalyzed Domino Cross-Coupling: Synthesis of Functionalized 4-(Arylethynyl)Coumarins

被引：8
|
作者：
Rao, Maddali L. N. [1 ]
Nand, Sachchida [1 ]
Murty, Venneti N. [1 ]
机构：
[1] Indian Inst Technol Kanpur, Dept Chem, Kanpur 208016, Uttar Pradesh, India
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 10卷 / 07期
关键词：
4-(gem-dibromovinyl)coumarin; triarylbismuth reagents; Pd-catalyzed domino cross-coupling; 4-(arylethynyl)coumarin; COUMARIN DERIVATIVES; TRIARYLBISMUTHS; DYE; EFFICIENCY;
D O I：
10.1002/ajoc.202100279
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Pd-catalyzed domino cross-coupling methodology was developed to synthesize various 4-(arylethynyl)coumarin derivatives involving 4-(gem-dibromovinyl)coumarins and triarylbismuths as threefold aryl donor reagents. In these reactions, 4-(gem-dibromovinyl)coumarin derivatives have been cross-coupled with sub-stoichiometric amounts of triarylbismuth reagents. This study involving mono-, chemoselective and bis-couplings have been demonstrated with versatile reactivity under the established Pd-catalyzed domino coupling conditions affording good to high product yields.
引用
收藏
页码：1822 / 1827
页数：6
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