A conceptual framework for a long-term economic model for the treatment of attention-deficit/hyperactivity disorder

被引:2
作者
Nagy, Balazs [1 ,2 ]
Setyawan, Juliana [3 ]
Coghill, David [4 ,5 ,6 ,7 ]
Soroncz-Szabo, Tamas [1 ]
Kalo, Zoltan [1 ,2 ]
Doshi, Jalpa A. [8 ,9 ]
机构
[1] Syreon Res Inst, Thokoly Str 119, H-1146 Budapest, Hungary
[2] Eotvos Lorand Univ, Dept Hlth Policy & Hlth Econ, Budapest, Hungary
[3] Shire, Global HEOR & Epidemiol, Wayne, PA USA
[4] Univ Dundee, Med Res Inst, Div Neurosci, Dundee, Scotland
[5] Ninewells Hosp & Med Sch, Dundee, Scotland
[6] Univ Melbourne, Royal Childrens Hosp, Fac Med Dent & Hlth Sci, Dept Paediat, Parkville, Vic, Australia
[7] Univ Melbourne, Royal Childrens Hosp, Fac Med Dent & Hlth Sci, Dept Psychiat, Parkville, Vic, Australia
[8] Univ Penn, Dept Med, Perelman Sch Med, Philadelphia, PA 19104 USA
[9] Univ Penn, Leonard Davis Inst Hlth Econ, Philadelphia, PA 19104 USA
关键词
ADHD; long-term model; conceptual model framework; long-term disease outcomes; ADHD therapy; DEFICIT HYPERACTIVITY DISORDER; COST-EFFECTIVENESS; SMOKING-CESSATION; LIFE-SPAN; ADHD; CARE; VARENICLINE; ADOLESCENTS; POPULATION; DEPRESSION;
D O I
10.1080/14737167.2017.1271325
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Background: Models incorporating long-term outcomes (LTOs) are not available to assess the health economic impact of attention-deficit/hyperactivity disorder (ADHD).Objective: Develop a conceptual modelling framework capable of assessing long-term economic impact of ADHD therapies.Methods: Literature was reviewed; a conceptual structure for the long-term model was outlined with attention to disease characteristics and potential impact of treatment strategies.Results: The proposed model has four layers: i) multi-state short-term framework to differentiate between ADHD treatments; ii) multiple states being merged into three core health states associated with LTOs; iii) series of sub-models in which particular LTOs are depicted; iv) outcomes collected to be either used directly for economic analyses or translated into other relevant measures.Conclusions: This conceptual model provides a framework to assess relationships between short- and long-term outcomes of the disease and its treatment, and to estimate the economic impact of ADHD treatments throughout the course of the disease.
引用
收藏
页码:283 / 292
页数:10
相关论文
共 35 条
[1]   A proposed model for economic evaluations of major depressive disorder [J].
Afzali, Hossein Haji Ali ;
Karnon, Jonathan ;
Gray, Jodi .
EUROPEAN JOURNAL OF HEALTH ECONOMICS, 2012, 13 (04) :501-510
[2]  
Alava M Hernandez, 2011, 94 SCHARR PUBL HLTH
[3]  
Alemi F, 2006, J MENT HEALTH POLICY, V9, P57
[4]   Cost Effectiveness of Varenicline in Belgium, Compared with Bupropion, Nicotine Replacement Therapy, Brief Counselling and Unaided Smoking Cessation A BENESCO Markov Cost-Effectiveness Analysis [J].
Annemans, Lieven ;
Nackaerts, Kristiaan ;
Bartsch, Pierre ;
Prignot, Jacques ;
Marbaix, Sophie .
CLINICAL DRUG INVESTIGATION, 2009, 29 (10) :655-665
[5]  
[Anonymous], J ATTENTION DISORDER
[6]  
ANTON SF, 1995, PSYCHOPHARMACOL BULL, V31, P249
[7]   ADHD from a socio-economic perspective [J].
Bernfort, Lars ;
Nordfeldt, Sam ;
Persson, Jan .
ACTA PAEDIATRICA, 2008, 97 (02) :239-245
[8]   Reducing the global burden of depression - Population-level analysis of intervention cost-effectiveness in 14 world regions [J].
Chisholm, D ;
Sanderson, K ;
Ayuso-Mateos, JL ;
Saxena, S .
BRITISH JOURNAL OF PSYCHIATRY, 2004, 184 :393-403
[9]   ASSESSMENT OF COSTS AND BENEFITS OF DRUG-THERAPY FOR TREATMENT-RESISTANT SCHIZOPHRENIA IN THE UNITED-KINGDOM [J].
DAVIES, LM ;
DRUMMOND, MF .
BRITISH JOURNAL OF PSYCHIATRY, 1993, 162 :38-42
[10]   Modeled Economic Evaluation of Alternative Strategies to Reduce Sudden Cardiac Death Among Children Treated for Attention Deficit/Hyperactivity Disorder [J].
Denchev, Peter ;
Kaltman, Jonathan R. ;
Schoenbaum, Michael ;
Vitiello, Benedetto .
CIRCULATION, 2010, 121 (11) :1329-1337