The thermal behavior of pyrazinamide in 12 solvents from 288.15 to 328.15 k

被引：7

作者：

Zhang, Jinyan ^{[1
]}

Liang, Zhihan ^{[1
]}

Ji, Shaochang ^{[2
]}

Wang, Xiaofang ^{[3
]}

Lan, Ping ^{[1
]}

机构：

[1] Guangxi Univ Nationalities, Guangxi Key Lab Polysaccharide Mat & Their Modifi, Coll Chem & Chem Engn, Key Lab Chem & Biol Transformat Proc Guangxi High, Nanning 530006, Guangxi, Peoples R China

[2] Guangxi Tobacco Monopoly Bur, Nanning 530006, Guangxi, Peoples R China

[3] Petrochina Dagang Oilfield, Petr Engn Res Inst, Tianjin 300000, Tianjin, Peoples R China

来源：

JOURNAL OF MOLECULAR LIQUIDS | 2021年 / 329卷

基金：

中国国家自然科学基金;

关键词：

Pyrazinamide; Solubility; Organic solvents; Thermodynamic models; THERMODYNAMIC PROPERTIES; RELATIVE STABILITY; ORGANIC-SOLVENTS; BINARY SOLVENTS; SOLUBILITY; ACID; POLYMORPHS; WATER; EQUILIBRIUM; LIMONIN;

D O I：

10.1016/j.molliq.2021.115572

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The solubility of pyrazinamide in twelve pure solvents was measured from 288.15k to 328.15k. The experimental data were correlated by the modified Apelblat model, lambda h equation, Wilson model and NRTL model, and the modified Apelblat model gave the best satisfactory fitting results. These solubility data of pyrazinamide presented in this paper can provide the basis for the optimization of its crystallization and the preparation of its cocrystals. (C) 2021 Elsevier B.V. All rights reserved.

引用

页数：6

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