Primary diffuse leptomeningeal melanomatosis: report of three pediatric cases and review of the literature

被引：4

作者：

Pezzullo, Giovanna ^{[1
]}

Ugga, Lorenzo ^{[1
]}

Cuocolo, Renato ^{[1
]}

Perillo, Teresa ^{[1
]}

D'Amico, Alessandra ^{[2
]}

机构：

[1] Univ Naples Federico II, Dept Adv Biomed Sci, Via Pansini 5, I-80131 Naples, Italy

[2] Tortorella Private Hosp, Radiol Dept, Salerno, Italy

来源：

MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY | 2021年 / 14卷 / 03期

关键词：

Leptomeningeal melanomatosis; Melanoma; Neuro-oncology; Magnetic resonance imaging; Pediatric oncology; CENTRAL-NERVOUS-SYSTEM; MALIGNANT-MELANOMA; MENINGEAL MELANOMATOSIS; METASTATIC MELANOMA; CEREBROSPINAL-FLUID; DIAGNOSIS; RARE; CLASSIFICATION; LESIONS; PET/CT;

D O I：

10.1007/s12254-021-00720-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Primary diffuse leptomeningeal melanomatosis is a rare and very aggressive neoplasm with only 6 pediatric cases reported so far. Recognizing this condition is unfortunately difficult due to the nonspecific clinical presentation. Nevertheless, imaging may help in a timely diagnosis that can better direct the management of these patients, especially in the light of the rapidly ominous course of the pathology. We describe three cases of pediatric primary diffuse leptomeningeal melanomatosis and review the literature regarding this entity, focusing on computed tomography and magnetic resonance imaging findings.

引用

页码：265 / 272

页数：8

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