Chemical Constituents of the Aerial Parts of Euphorbia nematocypha

被引：0

作者：

Xu, Chen ^{[1
]}

Jia, Hai-Yang ^{[1
]}

Zuo, Bo ^{[1
]}

Liao, Zhi-Xin ^{[1
]}

Ji, Lan-Ju ^{[2
]}

Sun, Hong-Fa ^{[2
]}

Wang, Qi ^{[3
]}

机构：

[1] Southeast Univ, Sch Chem & Chem Engn, Nanjing 211189, Jiangsu, Peoples R China

[2] Chinese Acad Sci, Northwest Inst Plateau Biol, Xining, Peoples R China

[3] Shihezi Univ, Sch Pharm, Key Lab XinJiang Phytomed Resources, Shihezi 832002, Peoples R China

来源：

NATURAL PRODUCT COMMUNICATIONS | 2016年 / 11卷 / 02期

关键词：

Euphorbia; Euphorbia nematocypha; Oleanane; Triterpenoid; Antiproliferative; DITERPENOIDS; ESTERS; ROOTS;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Chemical constituents of the dried aerial parts of Euphorbia nematocypha were investigated. A new oleanane triterpenoid, trans, trans-2',4'-hexadienedioicacid-1'-beta-amyrin ester (1), together with, beta-amyrin (2), beta-amyrin acetate (3), betulinic acid (4), ellagic acid (5), oleanolic acid (6), beta-sitosterol (7), kaempferol (8), quercetin (9), lupeol (10) and pseudo-taraxasterol (11) were isolated from the methylene chloride extract. Their structures were elucidated on the basis of extensive spectroscopic (1D- & 2D-NMR) and ESI-MS analysis and comparison with data reported in the literature. The new isolated triterpenoid showed moderate cytotoxic activities against HeLa and MCF-7cell lines.

引用

页码：177 / 178

页数：2

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