Curative effect of Yiqi Huoxue Tongmai decoction on in-stent restenosis after percutaneous coronary intervention in coronary heart disease

被引：0
作者：
Dai, Guofang [1 ]
Zhang, Jinying [2 ]
机构：
[1] First Hosp Tradit Chinese Med Luoyang, Dept Cardiol, Luoyang, Peoples R China
[2] Zhengzhou Univ, Affiliated Hosp 1, Dept Cardiol, 1 Construct East Rd, Zhengzhou, Henan, Peoples R China
来源：
BIOMEDICAL RESEARCH-INDIA | 2017年 / 28卷 / 10期
关键词：
Yiqi Huoxue Tongmai decoction; Coronary heart disease; Percutaneous coronary intervention; Restenosis; ARTERY-DISEASE; IMPLANTATION; EXPRESSION; TRIAL;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
This study aimed to investigate the curative effect of Yiqi Huoxue Tongmai decoction on In-Stent Restenosis (ISR) after Percutaneous Coronary Intervention (PCI) in Coronary Heart Disease (CHD). 95 cases of patients with ISR after PCI due to CHD were randomly divided into control group (46 cases) and Traditional Chinese Medicine (TCM) group (49 cases) who received conventional Western medicine therapy and therapy with Yiqi Huoxue Tongmai decoction based on conventional Western medicine therapy, respectively. After 12 months of treatment, the clinical efficacy, symptom scores, Electrocardiogram (ECG), coronary angiography, biochemical indexes in two groups were observed. Results showed that, the total clinical effective rate and total effective rate by ECG in TCM group were significantly higher than control group (P < 0.05). After treatment, the scores of chest pain, chest tightness, fatigue and dry mouth in TCM group were significantly lower than control group, respectively (P < 0.05); the ISR rate in TCM group was significantly lower than control group (P < 0.05); the blood lipid levels in TCM group were also significantly lower than those in control group (P < 0.05). Yiqi Huoxue Tongmai decoction has obvious curative effect on ISR after PCI in CHD patients, with no obvious adverse side effect.
引用
收藏
页码：4651 / 4656
页数：6
相关论文
共 17 条
[1]   Chinese Herbal Cardiotonic Pill Stabilizes Vulnerable Plaques in Rabbits by Decreasing the Expression of Adhesion Molecules [J].
Chen, Liang ;
Li, Xiaonan ;
Li, Changjiang ;
Rong, Yuanyuan ;
Xiao, Yawei ;
Xu, Xinsheng ;
Yao, Guihua ;
Jiang, Guihua ;
Zhang, Mei .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2016, 68 (03) :215-222
[2]  
Ellis SG, 1999, CIRCULATION, V100, P799
[3]   PRIMARY PREVENTION OF CORONARY HEART-DISEASE WITH DRUG-THERAPY - SAFETY AND TOTAL MORTALITY ISSUES [J].
GRUNDY, SM .
ARCHIVES OF INTERNAL MEDICINE, 1992, 152 (07) :1369-1371
[4]   Rotational atherectomy with adjunctive balloon angioplasty versus conventional percutaneous transluminal coronary angioplasty in type B2 lesions: Results of a randomized study [J].
Guerin, Y ;
Spaulding, C ;
Desnos, M ;
Funck, F ;
Rahal, S ;
Py, A ;
Besse, B ;
Tsocanakis, O ;
Guerin, F ;
Guerot, C .
AMERICAN HEART JOURNAL, 1996, 131 (05) :879-883
[5]   A preparation of herbal medicine Salvia miltiorrhiza reduces expression of intercellular adhesion molecule-1 and development of atherosclerosis in apolipoprotein E-deficient mice [J].
Ling, Shanhong ;
Dai, Aozhi ;
Guo, Zhixin ;
Komesaroff, Paul A. .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2008, 51 (01) :38-44
[6]   Percutaneous coronary intervention versus medical therapy for coronary heart disease. [J].
Maron D.J. .
Current Atherosclerosis Reports, 2000, 2 (4) :290-296
[7]   FASTTRACK -: Randomized trial of paclitaxel- and sirolimus-eluting stents in small coronary vessels [J].
Mehilli, J ;
Dibra, A ;
Kastrati, A ;
Pache, J ;
Dirschinger, J ;
Schömig, A .
EUROPEAN HEART JOURNAL, 2006, 27 (03) :260-266
[8]   High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation: A randomized controlled trial evaluating the relationship to endothelial function and inflammation [J].
Munk, Peter S. ;
Staal, Eva M. ;
Butt, Noreen ;
Isaksen, Kjetil ;
Larsen, Alf I. .
AMERICAN HEART JOURNAL, 2009, 158 (05) :734-741
[9]   Human vascular smooth muscle cells from restenosis or in-stent stenosis sites demonstrate enhanced responses to p53 - Implications for brachytherapy and drug treatment for restenosis [J].
Scott, S ;
O'Sullivan, M ;
Hafizi, S ;
Shapiro, LM ;
Bennett, MR .
CIRCULATION RESEARCH, 2002, 90 (04) :398-404
[10]   Persistent reservations against contradicted percutaneous coronary intervention indications: Citation content analysis [J].
Siontis, George C. M. ;
Tatsioni, Athina ;
Katritsis, Demosthenes G. ;
Ioannidis, John P. A. .
AMERICAN HEART JOURNAL, 2009, 157 (04) :695-701
12