Growth of dendritic spines: a continuing story

被引：93
作者：
Matus, A [1 ]
机构：
[1] Friedrich Miescher Inst, CH-4058 Basel, Switzerland
来源：
CURRENT OPINION IN NEUROBIOLOGY | 2005年 / 15卷 / 01期
关键词：
D O I：
10.1016/j.conb.2005.01.015
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Dendritic spines, which are present at the vast majority of excitatory synapses in the central nervous system, have a specialized cytoskeleton of dynamic actin filaments that makes them capable of rapid morphological plasticity. During development, structural remodeling of nascent spines is an important factor in experience-dependent shaping of neuronal circuits, whereas in the adult brain spines maintain a balance between morphological stability and plasticity.
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页码：67 / 72
页数：6
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