Stellate ganglion block reduces symptoms of Long COVID: A case series

被引:48
作者
Liu, Luke D. [1 ]
Duricka, Deborah L. [1 ]
机构
[1] Neuroversion Inc, Anchorage, AK 99508 USA
关键词
Long COVID/PASC; Myalgic encephalitis/chronic fatigue syndrome; (ME/CFS); Postural orthostatic tachycardia syndrome; (POTS); Dysautonomia; Stellate ganglion block; Cerebral blood flow; CEREBRAL-BLOOD-FLOW;
D O I
10.1016/j.jneuroim.2021.577784
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
After recovering from COVID-19, a significant proportion of symptomatic and asymptomatic individuals develop Long COVID. Fatigue, orthostatic intolerance, brain fog, anosmia, and ageusia/dysgeusia in Long COVID resemble "sickness behavior, " the autonomic nervous system response to pro-inflammatory cytokines (Dantzer et al., 2008). Aberrant network adaptation to sympathetic/parasympathetic imbalance is expected to produce long-standing dysautonomia. Cervical sympathetic chain activity can be blocked with local anesthetic, allowing the regional autonomic nervous system to "reboot. " In this case series, we successfully treated two Long COVID patients using stellate ganglion block, implicating dysautonomia in the pathophysiology of Long COVID and suggesting a novel treatment.
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页数:5
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