Copper-promoted N-cyclopropylation of anilines and amines by cyclopropylboronic acid

被引：49

作者：

Benard, Sebastien ^{[1
]}

Neuville, Luc ^{[1
]}

Zhu, Jieping ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, Ctr Rech Gif, F-91198 Gif Sur Yvette, France

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 19期

关键词：

CROSS-COUPLING REACTIONS; ARYLBORONIC ACIDS; C-N; CUPROUS CHLORIDE; BOND FORMATION; BIS(MU-OXO)DICOPPER COMPLEXES; CUPRIC ACETATE; CYCLIC AMIDES; MECHANISM; OXIDATION;

D O I：

10.1039/b925499d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reaction of anilines, primary and secondary aliphatic amines with cyclopropylboronic acid in dichloroethane in the presence of Cu(OAc)(2) (1 equiv.), 2,2'-bipyridine (1 equiv.) and sodium carbonate or sodium bicarbonate (2 equiv.) under air atmosphere afforded the corresponding N-cyclopropyl derivatives in good to excellent yields.

引用

页码：3393 / 3395

页数：3

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