Copper-promoted N-cyclopropylation of anilines and amines by cyclopropylboronic acid

被引：49
作者：
Benard, Sebastien [1 ]
Neuville, Luc [1 ]
Zhu, Jieping [1 ]
机构：
[1] CNRS, Inst Chim Subst Nat, Ctr Rech Gif, F-91198 Gif Sur Yvette, France
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 19期
关键词：
CROSS-COUPLING REACTIONS; ARYLBORONIC ACIDS; C-N; CUPROUS CHLORIDE; BOND FORMATION; BIS(MU-OXO)DICOPPER COMPLEXES; CUPRIC ACETATE; CYCLIC AMIDES; MECHANISM; OXIDATION;
D O I：
10.1039/b925499d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reaction of anilines, primary and secondary aliphatic amines with cyclopropylboronic acid in dichloroethane in the presence of Cu(OAc)(2) (1 equiv.), 2,2'-bipyridine (1 equiv.) and sodium carbonate or sodium bicarbonate (2 equiv.) under air atmosphere afforded the corresponding N-cyclopropyl derivatives in good to excellent yields.
引用
收藏
页码：3393 / 3395
页数：3
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