Enantioselective Synthesis of Alkyl Allyl Ethers via Palladium-Catalyzed Redox-Relay Heck Alkenylation of O-Alkyl Enol Ethers

被引：12

作者：

Prater, Matthew B. ^{[1
]}

Sigman, Matthew S. ^{[1
]}

机构：

[1] Univ Utah, Dept Chem, 315 S 1400 E, Salt Lake City, UT 84112 USA

来源：

ISRAEL JOURNAL OF CHEMISTRY | 2020年 / 60卷 / 3-4期

关键词：

Asymmetric Catalysis; C-C Coupling; Heck Reaction; ASYMMETRIC-SYNTHESIS; ETHERIFICATION; ARYLATIONS; ALKENOLS; ALCOHOLS; CARBONATES; MECHANISM; PHENOLS; INDOLES; ESTERS;

D O I：

10.1002/ijch.201900077

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein we report a transformation that generates an array of enantiomerically enriched, alkyl allyl ethers. Cyclic, acyclic, and heteroatom-bearing alkenyl triflates undergo an enantioselective, palladium-catalyzed C-C bond formation with diverse acyclic O-alkyl enol ethers in good yields and excellent enantioselectivities.

引用

页码：452 / 460

页数：9

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