The protective effects of dietary intake of flavonoids and its subclasses on metabolic syndrome incidence

被引：7

作者：

Hejazi, Jalal ^{[1
]}

Hosseinpour-Niazi, Somayeh ^{[2
]}

Yuzbashian, Emad ^{[3
]}

Mirmiran, Parvin ^{[4
]}

Azizi, Fereidoun ^{[5
]}

机构：

[1] Zanjan Univ Med Sci, Sch Med, Dept Nutr, Zanjan, Iran

[2] Shahid Beheshti Univ Med Sci, Nutr & Endocrine Res Ctr, Res Inst Endocrine Sci, POB 19395-4763, Tehran, Iran

[3] Univ Alberta, Dept Agr Food & Nutr Sci, Edmonton, AB, Canada

[4] Shahid Beheshti Univ Med Sci, Fac Nutr Sci & Food Technol, Natl Nutr & Food Technol Res Inst, Dept Clin Nutr & Dietet, Tehran, Iran

[5] Shahid Beheshti Univ Med Sci, Endocrine Res Ctr, Res Inst Endocrine Sci, Tehran, Iran

来源：

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION | 2022年 / 73卷 / 01期

关键词：

Flavonoids; metabolic syndrome; flavonols; flavones; LIFE-STYLE FACTORS; MEDITERRANEAN DIET; RELATIVE VALIDITY; RISK; ADULTS; METAANALYSIS; ASSOCIATION; POLYPHENOLS; RELIABILITY; DYSFUNCTION;

D O I：

10.1080/09637486.2021.1928008

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

This study aimed to evaluate the association between the intake of total flavonoids and flavonoid subclasses and metabolic syndrome (MetS) risk and to assess the modulating effects of lifestyle factors on these associations. A total of 1915 participants from the Tehran Lipid and Glucose Study were followed-up during 2006-2008 and 2016-2018. Their dietary intake was assessed by a food frequency questionnaire at baseline and within three-year intervals afterward. Moreover, the modifying effect of weight gain on the association between total flavonoids and MetS was assessed by Cox regression analysis. Participants in the highest tertile of flavonoid, flavonol, and flavone had a significantly lower MetS risk as compared to those in the lowest tertile. Also, in participants with weight gain <7%, all flavonoid subclasses had a more pronounced risk-reducing effect. Overall, the total flavonoid, flavonol, and flavone reduced the risk of MetS; this association could be modified by weight gain.

引用

页码：116 / 126

页数：11

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