In vitro activities of OPT-80 and comparator drugs against intestinal bacteria

被引：107
作者：
Finegold, SA
Molitoris, D
Vaisanen, ML
Song, YL
Liu, CX
Bolaños, M
机构：
[1] VA Greater Los Angeles Healthcare Syst, Med Serv, Los Angeles, CA USA
[2] VA Greater Los Angeles Healthcare Syst, Res Serv, Los Angeles, CA USA
[3] Univ Calif Los Angeles, Sch Med, Dept Med, Los Angeles, CA 90024 USA
[4] Univ Calif Los Angeles, Sch Med, Dept Microbiol Mol Genet & Immunol, Los Angeles, CA 90024 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 12期
关键词：
D O I：
10.1128/AAC.48.12.4898-4902.2004
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The activities of OPT-80 against 453 intestinal bacteria were compared with those of seven other drugs. OPT-80 showed good activity against most clostridia, staphylococci, and enterococci, but streptococci, aerobic and facultative gram-negative rods, anaerobic gram-negative rods, and Clostridium ramosum were resistant. Poor activity against anaerobic gram-negative rods may maintain colonization resistance.
引用
收藏
页码：4898 / 4902
页数：5
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