Case 19-2010: A 35-Year-Old Man with Adenocarcinoma of the Cecum.

被引：1

作者：

Ryan, David P. ^{[1
,5
]}

Engelman, Jeffrey A. ^{[1
,5
]}

Ferrone, Cristina R. ^{[2
,6
]}

Sahani, Dushyant V. ^{[3
,7
]}

Lisovsky, Mikhail ^{[4
,8
,9
,10
]}

机构：

[1] Massachusetts Gen Hosp, Div Hematol & Oncol, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Surg, Boston, MA 02114 USA

[3] Massachusetts Gen Hosp, Dept Radiol, Boston, MA 02114 USA

[4] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA

[5] Harvard Univ, Sch Med, Dept Med, Boston, MA USA

[6] Harvard Univ, Sch Med, Dept Surg, Boston, MA 02115 USA

[7] Harvard Univ, Sch Med, Dept Radiol, Boston, MA 02115 USA

[8] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

[9] Dartmouth Hitchcock Med Ctr, Dept Pathol, Lebanon, NH 03766 USA

[10] Dartmouth Coll, Hitchcock Med Ctr, Dartmouth Med Sch, Hanover, NH 03756 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2010年 / 362卷 / 25期

关键词：

METASTATIC COLORECTAL-CANCER; INITIAL TREATMENT; CHEMOTHERAPY; CETUXIMAB; MANAGEMENT; SURGERY;

D O I：

10.1056/NEJMcpc1003885

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 35-year-old man was seen in the outpatient cancer center at this hospital because of adenocarcinoma of the cecum. Three weeks earlier, he had passed bright red blood in the stool. Imaging studies revealed a mass in the cecum and the peritoneal and omental nodules. Colonoscopic-biopsy specimens of the cecal mass revealed adenocarcinoma. There was no family history of cancer. A management decision was made. © 2010 Massachusetts Medical Society.

引用

页码：2411 / 2419

页数：9

共 23 条

[1]

[Anonymous], 2002, AJCC CANC STAGING HD

[2] Management of bevacizumab-associated bowel perforation: a case series and review of the literature [J].

Badgwell, B. D. ;

Camp, E. R. ;

Feig, B. ;

Wolff, R. A. ;

Eng, C. ;

Ellis, L. M. ;

Cormier, J. N. .

ANNALS OF ONCOLOGY, 2008, 19 (03) :577-582

[3] The PI3K Pathway As Drug Target in Human Cancer [J].

Courtney, Kevin D. ;

Corcoran, Ryan B. ;

Engelman, Jeffrey A. .

JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (06) :1075-1083

[4] Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer [J].

Di Nicolantonio, Federica ;

Martini, Miriam ;

Molinari, Francesca ;

Sartore-Bianchi, Andrea ;

Arena, Sabrina ;

Saletti, Piercarlo ;

De Dosso, Sara ;

Mazzucchelli, Luca ;

Frattini, Milo ;

Siena, Salvatore ;

Bardelli, Alberto .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (35) :5705-5712

[5] Long-Term Survivors of Metastatic Colorectal Cancer Treated with Systemic Chemotherapy Alone: A North Central Cancer Treatment Group Review of 3811 Patients, N0144 [J].

Dy, Grace K. ;

Hobday, Timothy J. ;

Nelson, Garth ;

Windschitl, Harold E. ;

O'Connell, Michael J. ;

Alberts, Steven R. ;

Goldberg, Richard M. ;

Nikcevich, Daniel A. ;

Sargent, Daniel J. .

CLINICAL COLORECTAL CANCER, 2009, 8 (02) :88-93

[6] Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer [J].

Engelman, Jeffrey A. ;

Jaenne, Pasi A. .

CLINICAL CANCER RESEARCH, 2008, 14 (10) :2895-2899

[7] Targeting PI3K signalling in cancer: opportunities, challenges and limitations [J].

Engelman, Jeffrey A. .

NATURE REVIEWS CANCER, 2009, 9 (08) :550-562

[8] Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: A consensus statement [J].

Esquivel, J. ;

Sticca, R. ;

Sugarbaker, P. ;

Levine, E. ;

Yan, T. D. ;

Alexander, R. ;

Baratti, D. ;

Bartlett, D. ;

Barone, R. ;

Barrios, P. ;

Bieligk, S. ;

Bretcha-Boix, P. ;

Chang, C. K. ;

Chu, F. ;

Chu, Q. ;

Daniel, S. ;

deBree, E. ;

Deraco, M. ;

Dominguez-Parra, L. ;

Elias, D. ;

Flynn, R. ;

Foster, J. ;

Garofalo, A. ;

Gilly, F. N. ;

Glehen, O. ;

Gomez-Portilla, A. ;

Gonzalez-Bayon, L. ;

Gonzalez-Moreno, S. ;

Goodman, M. ;

Gushchin, V. ;

Hanna, N. ;

Hartmann, J. ;

Harrison, L. ;

Hoefer, R. ;

Kane, J. ;

Kecmanovic, D. ;

Kelley, S. ;

Kuhn, J. ;

LaMont, J. ;

Lange, J. ;

Li, B. ;

Loggie, B. ;

Mahteme, H. ;

Mann, G. ;

Martin, R. ;

Misih, R. A. ;

Moran, B. ;

Morris, D. ;

Onate-Ocana, L. ;

Petrelli, N. .

ANNALS OF SURGICAL ONCOLOGY, 2007, 14 (01) :128-133

[9] PHYSICAL-ACTIVITY, OBESITY, AND RISK FOR COLON-CANCER AND ADENOMA IN MEN [J].

GIOVANNUCCI, E ;

ASCHERIO, A ;

RIMM, EB ;

COLDITZ, GA ;

STAMPFER, MJ ;

WILLETT, WC .

ANNALS OF INTERNAL MEDICINE, 1995, 122 (05) :327-334

[10]

Jemal A, 2009, CA-CANCER J CLIN, V59, P225, DOI [10.3322/caac.20006, 10.3322/caac.21387]

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