Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function

被引:22
作者
Chen, Yandan [1 ]
Yao, Chunxu [1 ]
Teng, Yincheng [2 ]
Jiang, Rongzhen [2 ]
Huang, Xinxin [3 ]
Liu, Sheng [4 ]
Wan, Jun [4 ,5 ]
Broxmeyer, Hal E. [3 ]
Guo, Bin [1 ]
机构
[1] Shanghai Jiao Tong Univ, Key Lab Cell Differentiat & Apoptosis, Chinese Minist Educ, Dept Pathophysiol,Sch Med, Shanghai 200025, Peoples R China
[2] Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6, Dept Obstet & Gynecol, Inst Obstet & Gynecol, Obstetr Intens Care Ctr, Shanghai 200233, Peoples R China
[3] Indiana Univ Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA
[4] Indiana Univ Sch Med, CCBB, Dept Med & Mol Genet, Indianapolis, IN 46202 USA
[5] IUPUI, Sch Informat & Comp, Dept BioHlth Informat, Indianapolis, IN 46202 USA
关键词
PROGENITOR CELLS; TRANSPLANTATION;
D O I
10.1038/s41375-019-0528-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:2962 / 2966
页数:5
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