Comparison of monomeric and polymeric chiral stationary phases

被引：7

作者：

Lee, KP ^{[1
]}

Choi, SH

Kim, SY

Kim, TH

Ryoo, JJ

Ohta, K

Jin, JY

Takeuchi, T

Fujimoto, C

机构：

[1] Kyungpook Natl Univ, Grad Sch, Dept Chem, Taegu 702701, South Korea

[2] Natl Inst Adv Ind Sci & Technol, Ceram Res Inst, Moriyama Ku, Nagoya, Aichi 4638560, Japan

[3] Hamamatsu Univ Sch Med, Dept Chem, Hamamatsu, Shizuoka 4313192, Japan

[4] Gifu Univ, Fac Engn, Dept Chem, Gifu 5011193, Japan

[5] Gifu Univ, Instrumental Anal Ctr, Gifu 5011193, Japan

来源：

JOURNAL OF CHROMATOGRAPHY A | 2003年 / 987卷 / 1-2期

关键词：

chiral stationary phases; LC; surface grafting; retention factor; separation factor; amino acids; naphthylene methylethyl propanamide;

D O I：

10.1016/S0021-9673(02)01462-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Two-type polymeric chiral stationary phases (pCSPs) were prepared by surface grafting of chiral acryl-type monomers on a silica gel surface modified with 3-(trimethoxysilyl)propylmethacrylate. The prepared pCSPs were characterized by IR, FT-Raman, scanning electron microscopy, and elemental analysis. In addition, two-type monomeric chiral stationary phases (mCSPs) were also prepared. The racemic analytes were separated using the prepared mCSPs and pCSPs. The separation factor (alpha) and capacity factor (k(1)) of the racemic analytes for the pCSP and mCSP were compared. The alpha and k(1) values of the mCSP were higher than those of the pCSP. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：111 / 118

页数：8

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