Signal transduction - N-WASP regulation - the sting in the tail

被引：20

作者：

Fawcett, J

Pawson, T

机构：

[1] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada

[2] Univ Toronto, Dept Mol & Med Genet, Toronto, ON M5G 1X5, Canada

来源：

SCIENCE | 2000年 / 290卷 / 5492期

关键词：

D O I：

10.1126/science.290.5492.725

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：725 / 726

页数：2

共 7 条

[1] Activation by Cdc42 and PIP2 of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex [J].

Higgs, HN ;

Pollard, TD .

JOURNAL OF CELL BIOLOGY, 2000, 150 (06) :1311-1320

[2] Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein [J].

Kim, AS ;

Kakalis, LT ;

Abdul-Manan, M ;

Liu, GA ;

Rosen, MK .

NATURE, 2000, 404 (6774) :151-158

[3] Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP [J].

Miki, H ;

Sasaki, T ;

Takai, Y ;

Takenawa, T .

NATURE, 1998, 391 (6662) :93-96

[4]

Pawson T, 2000, GENE DEV, V14, P1027

[5] Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex [J].

Prehoda, KE ;

Scott, JA ;

Mullins, RD ;

Lim, WA .

SCIENCE, 2000, 290 (5492) :801-806

[6] Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4,5-bisphosphate [J].

Rohatgi, R ;

Ho, HYH ;

Kirschner, MW .

JOURNAL OF CELL BIOLOGY, 2000, 150 (06) :1299-1309

[7] The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly [J].

Rohatgi, R ;

Ma, L ;

Miki, H ;

Lopez, M ;

Kirchhausen, T ;

Takenawa, T ;

Kirschner, MW .

CELL, 1999, 97 (02) :221-231

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