Clinical outcome in neonates with twin anemia-polycythemia sequence

被引:46
作者
Lopriore, Enrico [1 ]
Slaghekke, Femke [2 ]
Oepkes, Dick [2 ]
Middeldorp, Johanna M. [2 ]
Vandenbussche, Frank P. [2 ]
Walther, Frans J. [1 ]
机构
[1] Leiden Univ, Med Ctr, Div Neonatol, Dept Pediat, Leiden, Netherlands
[2] Leiden Univ, Med Ctr, Div Fetal Med, Dept Obstet, Leiden, Netherlands
关键词
anemia; monochorionic twins; polycythemia; twin anemia-polycythemia sequence; twin-twin transfusion syndrome; FETOSCOPIC LASER-SURGERY; TRANSFUSION SYNDROME; MONOCHORIONIC TWINS; FETAL; ANASTOMOSES; CORDOCENTESIS; COMPLICATIONS; MANAGEMENT; ULTRASOUND; THERAPY;
D O I
10.1016/j.ajog.2010.02.032
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: The purpose of this study was to evaluate neonatal outcome of monochorionic twin pregnancies complicated by twin anemia-polycythemia sequence (TAPS). STUDY DESIGN: A cohort of consecutive monochorionic twins with TAPS with double survivors was included in the study. Each twin pair with TAPS was compared with 2 monochorionic twin pairs who were unaffected by TAPS or twin-to-twin transfusion syndrome and who were matched for gestational age at birth. Neonatal death, severe morbidity, and cerebral injury were studied. RESULTS: We included 19 twin pairs in the TAPS group and 38 control twin pairs. The incidence of neonatal death and severe neonatal morbidity was similar in the TAPS group and control group (3% [1/38] vs 1% [1/76] and 24% [9/38] vs 28% [21/76], respectively). Severe cerebral injury was detected in 1 infant (5%) in the TAPS group and 1 infant (2%) in the control group. CONCLUSION: Neonatal mortality and morbidity rates in a select population of TAPS neonates are similar to control neonatal rates.
引用
收藏
页码:54.e1 / 54.e5
页数:5
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