Entropy Analysis of RR and QT Interval Variability during Orthostatic and Mental Stress in Healthy Subjects

被引：19

作者：

Baumert, Mathias ^{[1
]}

Czippelova, Barbora ^{[2
]}

Ganesan, Anand ^{[3
]}

Schmidt, Martin ^{[4
]}

Zaunseder, Sebastian ^{[4
]}

Javorka, Michal ^{[2
]}

机构：

[1] Univ Adelaide, Sch Elect & Elect Engn, Adelaide, SA 5005, Australia

[2] Comenius Univ, Jessenius Fac Med, Dept Physiol, Martin 03601, Slovakia

[3] Univ Adelaide, Sch Med, Adelaide, SA 5005, Australia

[4] Tech Univ Dresden, Inst Biomed Engn, D-01069 Dresden, Germany

来源：

ENTROPY | 2014年 / 16卷 / 12期

基金：

澳大利亚研究理事会;

关键词：

QT variability; heart rate variability; stress; sympathetic; complexity; HEART-RATE-VARIABILITY; SAMPLE ENTROPY;

D O I：

10.3390/e16126384

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Autonomic activity affects beat-to-beat variability of heart rate and QT interval. The aim of this study was to explore whether entropy measures are suitable to detect changes in neural outflow to the heart elicited by two different stress paradigms. We recorded short-term ECG in 11 normal subjects during an experimental protocol that involved head-up tilt and mental arithmetic stress and computed sample entropy, cross-sample entropy and causal interactions based on conditional entropy from RR and QT interval time series. Head-up tilt resulted in a significant reduction in sample entropy of RR intervals and cross-sample entropy, while mental arithmetic stress resulted in a significant reduction in coupling directed from RR to QT. In conclusion, measures of entropy are suitable to detect changes in neural outflow to the heart and decoupling of repolarisation variability from heart rate variability elicited by orthostatic or mental arithmetic stress.

引用

页码：6384 / 6393

页数：10

共 23 条

[1] Multiscale Complexity Analysis of the Cardiac Control Identifies Asymptomatic and Symptomatic Patients in Long QT Syndrome Type 1 [J].

Bari, Vlasta ;

Valencia, Jose F. ;

Vallverdu, Montserrat ;

Girardengo, Giulia ;

Marchi, Andrea ;

Bassani, Tito ;

Caminal, Pere ;

Cerutti, Sergio ;

George, Alfred L., Jr. ;

Brink, Paul A. ;

Crotti, Lia ;

Schwartz, Peter J. ;

Porta, Alberto .

PLOS ONE, 2014, 9 (04)

[2] QT interval variability and cardiac norepinephrine spillover in patients with depression and panic disorder [J].

Baumert, Mathias ;

Lambert, Gavin W. ;

Dawood, Tye ;

Lambert, Elisabeth A. ;

Esler, Murray D. ;

McGrane, Mariee ;

Barton, David ;

Nalivaiko, Eugene .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2008, 295 (03) :H962-H968

[3] Decoupling of QT interval variability from heart rate variability with ageing [J].

Baumert, Mathias ;

Czippelova, Barbora ;

Porta, Alberto ;

Javorka, Michal .

PHYSIOLOGICAL MEASUREMENT, 2013, 34 (11) :1435-1448

[4] Conventional QT Variability Measurement vs. Template Matching Techniques: Comparison of Performance Using Simulated and Real ECG [J].

Baumert, Mathias ;

Starc, Vito ;

Porta, Alberto .

PLOS ONE, 2012, 7 (07)

[5] Multiscale entropy and detrended fluctuation analysis of QT interval and heart rate variability during normal pregnancy [J].

Baumert, Mathias ;

Javorka, Michal ;

Seeck, Andrea ;

Faber, Renaldo ;

Sanders, Prashanthan ;

Voss, Andreas .

COMPUTERS IN BIOLOGY AND MEDICINE, 2012, 42 (03) :347-352

[6] Relation between QT interval variability and cardiac sympathetic activity in hypertension [J].

Baumert, Mathias ;

Schlaich, Markus P. ;

Nalivaiko, Eugene ;

Lambert, Elisabeth ;

Sari, Carolina Ika ;

Kaye, David M. ;

Elser, Murray D. ;

Sanders, Prashanthan ;

Lambert, Gavin .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2011, 300 (04) :H1412-H1417

[7] Beat-to-beat QT interval variability - Novel evidence for repolarization lability in ischemic and nonischemic dilated cardiomyopathy [J].

Berger, RD ;

Kasper, EK ;

Baughman, KL ;

Marban, E ;

Calkins, H ;

Tomaselli, GF .

CIRCULATION, 1997, 96 (05) :1557-1565

[8] Time Delay Estimation: A New Insight Into the Woody's Method [J].

Cabasson, Aline ;

Meste, Olivier .

IEEE SIGNAL PROCESSING LETTERS, 2008, 15 :573-576

[9] Mechanisms of causal interaction between short-term RR interval and systolic arterial pressure oscillations during orthostatic challenge [J].

Faes, Luca ;

Nollo, Giandomenico ;

Porta, Alberto .

JOURNAL OF APPLIED PHYSIOLOGY, 2013, 114 (12) :1657-1667

[10] Information domain approach to the investigation of cardio-vascular, cardio-pulmonary, and vasculo-pulmonary causal couplings [J].

Faes, Luca ;

Nollo, Giandomenico ;

Porta, Alberto .

FRONTIERS IN PHYSIOLOGY, 2011, 2

← 1 2 3 →