Background: In the process of English teaching, due to various reasons, some students' English performance is not ideal, and students are prone to anxiety, which is not conducive to students' personal development. Positive psychology advocates the positive orientation of psychology, mainly studies the positive psychological quality of individuals, human health and happiness and the harmonious development of society, and advocates an open and encouraging attitude to treat individual potential, motivation and emotion, so as to realize the transformation of individuals from negative psychological mode to positive psychological mode. The research is based on positive psychology to innovate and improve college English teaching mode, so as to improve students' enthusiasm, alleviate students' mania, loneliness and other negative emotions, and then alleviate students' anxiety symptoms, so as to provide guarantee for students' long-term development. Subjects and methods: To innovate and improve college English teaching model based on positive psychology, so as to improve students' enthusiasm and alleviate students' anxiety symptoms. 120 students were randomly selected from a university as the research object. Self-rating Anxiety Scale (SAS) was used to evaluate students' mental health. Students were randomly divided into study group and control group. The students in the research group adopted an innovative English teaching model. The students in the control group adopted the traditional teaching mode. Methods: the relevant data were processed and statistically analyzed by SPSS21.0 software. Results: After teaching, the SAS score of the students in the research group was significantly lower than that in the control group (P > 0.05). Conclusions: The innovation of college English teaching model based on positive psychology can significantly improve students' positive psychology of English learning, improve students' English performance, alleviate negative emotions and anxiety symptoms, which is of positive significance to students' personal development.