Inclusion complex characterization between progesterone and hydroxypropyl-β-cyclodextrin in aqueous solution by NMR study

被引：16

作者：

Torri, Giangiacomo

Bertini, Sabrina

Giavana, Tania

Guerrini, Marco

Puppini, Nadia

Zoppetti, Giorgio

机构：

[1] Inst Chem & Biochem Res G Ronzoni, I-20133 Milan, Italy

[2] IBSA SA, CH-6915 Pambio Noranco, Switzerland

来源：

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY | 2007年 / 57卷 / 1-4期

关键词：

inclusion complex; NMR; cyclodextrin; HP beta CD; progesterone;

D O I：

10.1007/s10847-006-9180-4

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The aim of this work is the determination of the molecular association of progesterone (P) with hydroxypropyl-beta-cyclodextrin (HP beta CD) in aqueous solution. The stoichiometry and the binding constants of the inclusion complex were calculated using NMR techniques.

引用

页码：317 / 321

页数：5

共 6 条

[1]

CONNORS KA, 1987, BINDING CONSTANTS ME, P198

[2] A study of β-cyclodextrin inclusion complexes with progesterone and hydrocortisone using rotating frame Overhauser spectroscopy [J].