Hydrogels and Their Role in Biosensing Applications

被引：182
作者：
Herrmann, Anna [1 ]
Haag, Rainer [1 ]
Schedler, Uwe [2 ]
机构：
[1] Free Univ Berlin, Dept Biol Chem Pharm, Takustr 3, D-14195 Berlin, Germany
[2] PolyAn GmbH, Rudolf Baschant Str 2, D-13086 Berlin, Germany
来源：
ADVANCED HEALTHCARE MATERIALS | 2021年 / 10卷 / 11期
关键词：
bioassays; biosensing; hybridization assays; hydrogels; immunoassays; wearables;
D O I：
10.1002/adhm.202100062
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Hydrogels play an important role in the field of biomedical research and diagnostic medicine. They are emerging as a powerful tool in the context of bioanalytical assays and biosensing. In this context, this review gives an overview of different hydrogels and the role they adopt in a range of applications. Not only are hydrogels beneficial for the immobilization and embedding of biomolecules, but they are also used as responsive material, as wearable devices, or as functional material. In particular, the scientific and technical progress during the last decade is discussed. The newest hydrogel types, their synthesis, and many applications are presented. Advantages and performance improvements are described, along with their limitations.
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页数：25
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  • [1] Electrically Conducting Hydrogels for Health care: Concept, Fabrication Methods, and Applications
    Agarwala, Shweta
    [J]. INTERNATIONAL JOURNAL OF BIOPRINTING, 2020, 6 (02) : 1 - 15
  • [2] Gradient Hydrogel Matrix for Microarray and Biosensor Applications: An Imaging SPR Study
    Andersson, Olof
    Larsson, Andreas
    Ekblad, Tobias
    Liedberg, Bo
    [J]. BIOMACROMOLECULES, 2009, 10 (01) : 142 - 148
  • [3] Protein microchips: Use for immunoassay and enzymatic reactions
    Arenkov, P
    Kukhtin, A
    Gemmell, A
    Voloshchuk, S
    Chupeeva, V
    Mirzabekov, A
    [J]. ANALYTICAL BIOCHEMISTRY, 2000, 278 (02) : 123 - 131
  • [4] Biopolymeric Mucin and Synthetic Polymer Analogs: Their Structure, Function and Role in Biomedical Applications
    Authimoolam, Sundar P.
    Dziubla, Thomas D.
    [J]. POLYMERS, 2016, 8 (03)
  • [5] A Biosensor for Aromatic Aldehydes Comprising the Mediator Dependent PaoABC-Aldehyde Oxidoreductase
    Badalyan, Artavazd
    Neumann-Schaal, Meina
    Leimkuehler, Silke
    Wollenberger, Ulla
    [J]. ELECTROANALYSIS, 2013, 25 (01) : 101 - 108
  • [6] Tailored hydrogels for biosensor applications
    Bae, Joonwon
    Park, Jongnam
    Kim, Seongsoo
    Cho, Hana
    Kim, Hye Jun
    Park, Soyeon
    Shin, Dong-Sik
    [J]. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2020, 89 : 1 - 12
  • [7] Wearable Sensors for Biochemical Sweat Analysis
    Bandodkar, Amay J.
    Jeang, William J.
    Ghaffari, Roozbeh
    Rogers, John A.
    [J]. ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 12, 2019, 12 : 1 - 22
  • [8] Hydrogel particles improve detection of SARS-CoV-2 RNA from multiple sample types
    Barclay, R. A.
    Akhrymuk, I.
    Patnaik, A.
    Callahan, V.
    Lehman, C.
    Andersen, P.
    Barbero, R.
    Barksdale, S.
    Dunlap, R.
    Goldfarb, D.
    Jones-Roe, T.
    Kelly, R.
    Kim, B.
    Miao, S.
    Munns, A.
    Munns, D.
    Patel, S.
    Porter, E.
    Ramsey, R.
    Sahoo, S.
    Swahn, O.
    Warsh, J.
    Kehn-Hall, K.
    Lepene, B.
    [J]. SCIENTIFIC REPORTS, 2020, 10 (01)
  • [9] A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering
    Billiet, Thomas
    Vandenhaute, Mieke
    Schelfhout, Jorg
    Van Vlierberghe, Sandra
    Dubruel, Peter
    [J]. BIOMATERIALS, 2012, 33 (26) : 6020 - 6041
  • [10] Kinetics of the urea-urease clock reaction with urease immobilized in hydrogel beads
    Bubanja, Itana Nusa
    Bansagi, Tamas, Jr.
    Taylor, Annette Fiona
    [J]. REACTION KINETICS MECHANISMS AND CATALYSIS, 2018, 123 (01) : 177 - 185
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