Growth Hormone and Endometrial Receptivity

被引：28

作者：

Altmae, Signe ^{[1
,2
,3
]}

Aghajanova, Lusine ^{[4
]}

机构：

[1] Univ Granada, Fac Sci, Dept Biochem & Mol Biol, Granada, Spain

[2] Competence Ctr Hlth Technol, Tartu, Estonia

[3] Inst Invest Biosanitaria Ibs GRANADA, Granada, Spain

[4] Stanford Sch Med, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Sunnyvale, CA USA

来源：

FRONTIERS IN ENDOCRINOLOGY | 2019年 / 10卷

关键词：

endometrium; endometrial receptivity; growth hormone; infertility; in vitro fertilization; transcriptome; IN-VITRO FERTILIZATION; REPEATED IMPLANTATION FAILURE; AGONIST LONG PROTOCOL; POOR RESPONDERS; EMBRYO IMPLANTATION; UTERINE RECEPTIVITY; GENE-EXPRESSION; PROGESTERONE PRODUCTION; OVARIAN STIMULATION; ANTAGONIST PROTOCOL;

D O I：

10.3389/fendo.2019.00653

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Administration of growth hormone (GH) during ovarian stimulation has shown beneficial effects on in vitro fertilization (IVF) outcomes. It is generally believed that this improvement is due to the stimulating effect of GH on oocyte quality. However studies are emerging that show possible positive effect of GH administration on endometrial receptivity, thus suggesting an additional potential benefit at the level of the uterus, especially among women with recurrent implantation failure, thin endometrium, and older normal responders. This review summarizes recent data on GH co-treatment effects on endometrium and endometrial receptivity among infertile women undergoing IVF, and proposes possible mechanisms of GH actions in the endometrium.

引用

页数：11

共 68 条

[1] ENDOMETRIAL THICKNESS - A PREDICTOR OF IMPLANTATION IN OVUM RECIPIENTS [J].

ABDALLA, HI ;

BROOKS, AA ;

JOHNSON, MR ;

KIRKLAND, A ;

THOMAS, A ;

STUDD, JWW .

HUMAN REPRODUCTION, 1994, 9 (02) :363-365

[2] Endometrial gene expression analysis at the time of embryo implantation in women with unexplained infertility [J].

Altmae, S. ;

Martinez-Conejero, J. A. ;

Salumets, A. ;

Simon, C. ;

Horcajadas, J. A. ;

Stavreus-Evers, A. .

MOLECULAR HUMAN REPRODUCTION, 2010, 16 (03) :178-187

[3] Effect of Growth Hormone on Uterine Receptivity in Women With Repeated Implantation Failure in an Oocyte Donation Program: A Randomized Controlled Trial [J].

Altmae, Signe ;

Mendoza-Tesarik, Raquel ;

Mendoza, Carmen ;

Mendoza, Nicolas ;

Cucinelli, Francesco ;

Tesarik, Jan .

JOURNAL OF THE ENDOCRINE SOCIETY, 2018, 2 (01) :96-105

[4] Research Resource: Interactome of Human Embryo Implantation: Identification of Gene Expression Pathways, Regulation, and Integrated Regulatory Networks [J].

Altmae, Signe ;

Reimand, Jueri ;

Hovatta, Outi ;

Zhang, Pu ;

Kere, Juha ;

Laisk, Triin ;

Saare, Merli ;

Peters, Maire ;

Vilo, Jaak ;

Stavreus-Evers, Anneli ;

Salumets, Andres .

MOLECULAR ENDOCRINOLOGY, 2012, 26 (01) :203-217

[5] Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium [J].

Altmaee, Signe ;

Esteban, Francisco J. ;

Stavreus-Evers, Anneli ;

Simon, Carlos ;

Giudice, Linda ;

Lessey, Bruce A. ;

Horcajadas, Jose A. ;

Macklon, Nick S. ;

D'Hooghe, Thomas ;

Campoy, Cristina ;

Fauser, Bart C. ;

Salamonsen, Lois A. ;

Salumets, Andres .

HUMAN REPRODUCTION UPDATE, 2014, 20 (01) :12-28

[6] Does the addition of growth hormone to the in vitro fertilization/intracytoplasmic sperm injection antagonist protocol improve outcomes in poor responders? A randomized, controlled trial [J].

Bassiouny, Yasmin Ahmed ;

Dakhly, Dina Mohamed Refaat ;

Bayoumi, Yomna Ali ;

Hashish, Nawara Mohamed .

FERTILITY AND STERILITY, 2016, 105 (03) :697-702

[7] Addition of growth hormone to the microflare stimulation protocol among women with poor ovarian response [J].

Bayoumi, Yomna A. ;

Dakhly, Dina M. R. ;

Bassiouny, Yasmin A. ;

Hashish, Nawara M. .

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2015, 131 (03) :305-308

[8] INDEPENDENT CONTROL OF THE PRODUCTION OF INSULIN-LIKE GROWTH FACTOR-I AND ITS BINDING-PROTEIN BY CULTURED TESTICULAR CELLS [J].

CAILLEAU, J ;

VERMEIRE, S ;

VERHOEVEN, G .

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1990, 69 (01) :79-89

[9] Changes in gene expression during the early to mid-luteal (receptive phase) transition in human endometrium detected by high-density microarray screening [J].

Carson, DD ;

Lagow, E ;

Thathiah, A ;

Al-Shami, R ;

Farach-Carson, MC ;

Vernon, M ;

Yuan, LW ;

Fritz, MA ;

Lessey, B .

MOLECULAR HUMAN REPRODUCTION, 2002, 8 (09) :871-879

[10] Growth hormone signaling pathways [J].

Carter-Su, Christin ;

Schwartz, Jessica ;

Argetsinger, Lawrence S. .

GROWTH HORMONE & IGF RESEARCH, 2016, 28 :11-15

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