Neuro-ophthalmological manifestations of sarcoidosis

被引:5
作者
Yates, William B. [1 ,2 ]
McCluskey, Peter J. [1 ,2 ]
Fraser, Clare L. [1 ,2 ]
机构
[1] Univ Sydney, Save Sight Inst, Sydney, Australia
[2] Sydney Eye Hosp, Dept Ophthalmol, Sydney, Australia
关键词
Sarcoidosis; Neuro-ophthalmic sarcoidosis; Uveitis; Ocular immunology; OCULAR SARCOIDOSIS; DIAGNOSIS; FEATURES; NEUROSARCOIDOSIS;
D O I
10.1016/j.jneuroim.2022.577851
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Neuro-sarcoidosis has important ophthalmic and neuro-ophthalmic manifestations. Sarcoidosis most commonly affects the uveal tract (iris, ciliary body, and choroid) however the optic nerve is commonly involved. Sarcoid related optic neuritis is an important differential diagnosis in optic neuritis especially in atypical presentations. The use of multimodal imaging techniques available in the ophthalmic setting can enable the detection of choroidal or optic nerve granulomas and aid the diagnosis. Efferent manifestations of neuro-sarcoidosis are broad and can range from isolated cranial neuropathies or multiple as well as pupil abnormalities. Currently to date there are no diagnostic framework to assist in the diagnosis of ophthalmic manifestations in neuro-sarcoidosis in the absence of a tissue biopsy.
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页数:7
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