Targeted Vaccine Allocation Could Increase the COVID-19 Vaccine Benefits Amidst Its Lack of Availability: A Mathematical Modeling Study in Indonesia

被引:30
作者
Fuady, Ahmad [1 ,2 ]
Nuraini, Nuning [3 ,4 ]
Sukandar, Kamal K. [3 ]
Lestari, Bony W. [4 ,5 ,6 ]
机构
[1] Univ Indonesia, Fac Med, Dept Community Med, Jakarta 10310, Indonesia
[2] Erasmus MC Univ Med Ctr Rotterdam, Dept Publ Hlth, NL-3015 GD Rotterdam, Netherlands
[3] Inst Teknol Bandung, Dept Math, Bandung 40132, Indonesia
[4] Epidemiol Grp COVID 19 Task Force West Java, Bandung 40171, Indonesia
[5] Univ Padjadjaran, Fac Med, Dept Publ Hlth, Bandung 40161, Indonesia
[6] Radboud Univ Nijmegen, Med Ctr, Dept Internal Med, NL-6525 GA Nijmegen, Netherlands
关键词
COVID-19; vaccine; strategy; modeling; low- and middle-income countries; STRATEGIES;
D O I
10.3390/vaccines9050462
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
With a limited number of vaccines and healthcare capacity shortages, particularly in low- and middle-income countries, vaccination programs should seek the most efficient strategy to reduce the negative impact of the COVID-19 pandemics. This study aims at assessing several scenarios of delivering the vaccine to people in Indonesia. We develop a model for several scenarios of delivering vaccines: without vaccination, fair distribution, and targeted distribution to five and eight districts with the highest COVID-19 incidence in West Java, one of the most COVID-19-affected regions in Indonesia. We calculate the needs of vaccines and healthcare staff for the program, then simulate the model for the initial 4-month and one-year scenarios. A one-year vaccination program would require 232,000 inoculations per day by 4833 vaccinators. Targeted vaccine allocation based on the burden of COVID-19 cases could benefit the COVID-19 vaccination program by lowering at least 5000 active cases. The benefits would increase by improving the number of vaccines and healthcare staff. Amidst lacking available vaccines, targeted vaccine allocation based on the burden of COVID-19 cases could increase the benefit of the COVID-19 vaccination program but still requires progressive efforts to improve healthcare capacity and vaccine availability for optimal protection for people.
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页数:10
相关论文
共 26 条
[1]  
[Anonymous], 2020, CEPI
[2]  
Baker T., 2020, COVID 19 AFTERSHOCKS
[3]   Monitoring approaches for health-care workers during the COVID-19 pandemic [J].
Bielicki, Julia A. ;
Duval, Xavier ;
Gobat, Nina ;
Goossens, Herman ;
Koopmans, Marion ;
Tacconelli, Evelina ;
van der Werf, Sylvie .
LANCET INFECTIOUS DISEASES, 2020, 20 (10) :E261-E267
[4]   Model-informed COVID-19 vaccine prioritization strategies by age and serostatus [J].
Bubar, Kate M. ;
Reinholt, Kyle ;
Kissler, Stephen M. ;
Lipsitch, Marc ;
Cobey, Sarah ;
Grad, Yonatan H. ;
Larremore, Daniel B. .
SCIENCE, 2021, 371 (6532) :916-+
[5]  
Burgos Rodrigo M, 2021, Drugs Context, V10, DOI 10.7573/dic.2020-12-2
[6]   Urgent needs of low-income and middle-income countries for COVID-19 vaccines and therapeutics [J].
Figueroa, J. Peter ;
Bottazzi, Maria Elena ;
Hotez, Peter ;
Batista, Carolina ;
Ergonul, Onder ;
Gilbert, Sarah ;
Gursel, Mayda ;
Hassanain, Mazen ;
Kim, Jerome H. ;
Lall, Bhavna ;
Larson, Heidi ;
Naniche, Denise ;
Sheahan, Timothy ;
Shoham, Shmuel ;
Wilder-Smith, Annelies ;
Strub-Wourgaft, Natalie ;
Yadav, Prashant ;
Kang, Gagandeep .
LANCET, 2021, 397 (10274) :562-564
[7]   Comparing COVID-19 vaccine allocation strategies in India: A mathematical modelling study [J].
Foy, Brody H. ;
Wahl, Brian ;
Mehta, Kayur ;
Shet, Anita ;
Menon, Gautam, I ;
Britto, Carl .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2021, 103 :431-438
[8]  
Fuady A., 2019, ARSITEKTUR JAMINAN K
[9]  
Gayle H., 2020, FRAMEWORK EQUITABLE, V10
[10]   Vaccinating the oldest against COVID-19 saves both the most lives and most years of life [J].
Goldstein, Joshua R. ;
Cassidy, Thomas ;
Wachter, Kenneth W. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (11)