Gelation behavior of Antheraea pernyi silk fibroin

被引:16
作者
Yan ShuQin
Zhao ChunXia
Wu XiuFang
Zhang Qiang
Li MingZhong [1 ]
机构
[1] Soochow Univ, Natl Engn Lab Modern Silk, Suzhou 215123, Peoples R China
基金
中国国家自然科学基金;
关键词
Antheraea pernyi; silk fibroin; gelation; sol-gel transition; FIBROBLAST CELLS; GROWTH; ATTACHMENT; HYDROGELS; BIOMATERIALS; DISSOLUTION; SCAFFOLDS; FILM;
D O I
10.1007/s11426-010-0093-0
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The sol-gel transition behavior of Antherae pernyi silk fibroin (Ap-SF) has not been systematically investigated. In this work, the influence of environmental temperature, pH, the concentration of Ap-SF, K+ and Ca2+ on the gelation time, and the structural changes of Ap-SF in sol-gel transformation were studied. The results indicated that the gelation time of the Ap-SF aqueous solution decreased with the increase of the Ap-SF concentration and environmental temperature. The sol-gel transformation of Ap-SF was much more rapid than that of Bombyx mori silk fibroin under the same conditions. The Ap-SF was sensitive to changes in the concentration of Ca2+ and K+. Upon gelation, the random coil structure of the Ap-SF was significantly transformed into the beta-sheet structure.
引用
收藏
页码:535 / 541
页数:7
相关论文
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