Recognizing the reagent microbiome

被引:221
作者
de Goffau, Marcus C. [1 ]
Lager, Susanne [2 ,3 ]
Salter, Susannah J. [1 ]
Wagner, Josef [1 ]
Kronbichler, Andreas [4 ,5 ]
Charnock-Jones, D. Stephen [2 ,3 ]
Peacock, Sharon J. [1 ,6 ,7 ]
Smith, Gordon C. S. [2 ,3 ]
Parkhill, Julian [1 ]
机构
[1] Wellcome Sanger Inst, Cambridge, England
[2] Univ Cambridge, NIHR Cambridge Comprehens Biomed Res Ctr, Dept Obstet & Gynaecol, Cambridge, England
[3] Univ Cambridge, Dept Physiol Dev & Neurosci, CTR, Cambridge, England
[4] Med Univ Innsbruck, Dept Internal Med Nephrol & Hypertens 4, Innsbruck, Austria
[5] Addenbrookes Hosp, Vasculitis & Lupus Clin, Cambridge, England
[6] Univ Cambridge, Dept Med, Cambridge, England
[7] London Sch Hyg & Trop Med, London, England
来源
NATURE MICROBIOLOGY | 2018年 / 3卷 / 08期
基金
英国医学研究理事会;
关键词
DIVERSITY; SEQUENCE;
D O I
10.1038/s41564-018-0202-y
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A noticeable part of the microbiome literature, especially that working with low-biomass samples, is plagued by reagent contamination. Here we describe visual, statistical, methodical and ecological techniques to facilitate recognition of signals that represent contamination.
引用
收藏
页码:851 / 853
页数:3
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