Synthesis of N1 and N2 coumarin substituted 1,2,3-triazole isomers via click chemistry approach

被引：20

作者：

Shamala, Devadas ^{[1
]}

Shivashankar, Kalegowda ^{[1
]}

Chandra ^{[2
]}

Mahendra, Madegowda ^{[2
]}

机构：

[1] Bangalore Univ, PG Dept Chem, Cent Coll Campus, Bangalore 560001, Karnataka, India

[2] Univ Mysore, Dept Studies Phys, Mysore, Karnataka, India

来源：

SYNTHETIC COMMUNICATIONS | 2016年 / 46卷 / 05期

关键词：

Azide; 4-bromomethylcoumarins; click chemistry; copper iodide; coumarins; triazoles; ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; REGIOSELECTIVE SYNTHESIS; TRIAZOLE DERIVATIVES; 3-COMPONENT REACTION; SODIUM-AZIDE; ARYLATION; CHLORIDES; DESIGN;

D O I：

10.1080/00397911.2016.1140785

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of N-1 and N-2 coumarin substituted 1,2,3-triazole isomers from terminal alkynes, sodium azide, and 4-bromomethylcoumarins in the presence of triethylamine as a base and CuI as a catalyst in good yield are reported. The molecular structure of compounds 3g and 5d are established by single-crystal analysis.

引用

页码：433 / 441

页数：9

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