INVESTIGATED THE SUPRAMOLECULAR INTERACTION OF TRAMADOL HYDROCHLORIDE WITH P-SULFONATED CALIX[4,6,8]ARENE

被引：4

作者：

Zhao, Qing-Hua ^{[1
]}

Chen, Cai-Ping ^{[1
]}

Pang, Tao-Tao ^{[1
]}

Du, Li-Ming ^{[1
]}

Li, Yan ^{[1
]}

Xie, Jian-Hong ^{[1
]}

Fu, Yun-Long ^{[1
]}

机构：

[1] Shanxi Normal Univ, Sch Chem & Mat Sci, Linfen 041004, Shanxi, Peoples R China

来源：

JOURNAL OF THE CHILEAN CHEMICAL SOCIETY | 2015年 / 60卷 / 04期

基金：

中国国家自然科学基金; 高等学校博士学科点专项科研基金;

关键词：

Tramadol hydrochloride; Spectrofluorometry; Supramolecular interaction; p-sulfonated calyx[n]arene; INCLUSION INTERACTION; O-DESMETHYLTRAMADOL; HPLC DETERMINATION; AMINO-ACIDS; COMPLEXATION; VALIDATION; PLASMA; IONS;

D O I：

10.4067/S0717-97072015000400007

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper, the interaction behavior of p-sulfonated calix[n]arene (SCnA) with tramadol hydrochloride was investigated by fluorescence spectra, H-1 NMR spectra, and theoretical calculations in aqueous solution. At the optimized conditions, the fluorescence intensity of tramadol hydrochloride showed positive correlation to the concentration of SCnA, which led to a validated, simple, and sensitive fluorescence quenching method for the determination of tramadol hydrochloride was established for the first time. Moreover, the interaction based on SCnA superstructure provided has promising potential for therapeutic monitoring and pharmacokinetics and clinical application

引用

页码：2659 / 2663

页数：5

共 38 条

[21] Considerable fluorescence enhancement upon supramolecular complex formation between berberine and p-sulfonated calixarenes [J].

Megyesi, Monika ;

Biczok, Lazlo .

CHEMICAL PHYSICS LETTERS, 2006, 424 (1-3) :71-76

[22] Complexation and separation of amines, amino acids, and peptides by functionalized calix[n]arenes [J].

Mutihac, L ;

Buschmann, HJ ;

Mutihac, RC ;

Schollmeyer, E .

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 2005, 51 (1-2) :1-10

[23] High-performance liquid chromatographic determination of tramadol and its O-desmethylated metabolite in blood plasma -: Application to a bioequivalence study in humans [J].

Nobilis, M ;

Kopecky, J ;

Kvetina, J ;

Chládek, J ;

Svoboda, Z ;

Vorísek, V ;

Perlík, F ;

Pour, M ;

Kunes, J .

JOURNAL OF CHROMATOGRAPHY A, 2002, 949 (1-2) :11-22

[24] An accurate, rapid and sensitive determination of tramadol and its active metabolite O-desmethyltramadol in human plasma by LC-MS/MS [J].

Patel, Bhavin N. ;

Sharma, Naveen ;

Sanyal, Mallika ;

Shrivastav, Pranav S. .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2009, 49 (02) :354-366

[25] Removal of uranyl ions by p-hexasulfonated calyx[6]arene acid [J].

Popescu, Ioana-Carmen ;

Petru, Filip ;

Humelnicu, Ionel ;

Mateescu, Marina ;

Militaru, Ecaterina ;

Humelnicu, Doina .

JOURNAL OF NUCLEAR MATERIALS, 2014, 453 (1-3) :75-81

[26] Development and validation of a rapid HPLC method for simultaneous determination of tramadol, and its two main metabolites in human plasma [J].

Rouini, MR ;

Ardakani, YH ;

Soltani, F ;

Aboul-Enein, HY ;

Foroumadi, A .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2006, 830 (02) :207-211

[27] Studies of morphological optical and electrical properties of the MEH-PPV/azo-calix[4]arene composite layers [J].

Rouis, A. ;

Davenas, J. ;

Bonnamour, I. ;

Ben Ouada, H. .

PHYSICA B-CONDENSED MATTER, 2015, 474 :70-76

[28] Capability of parasulfonato calix[6]arene, as an anion dopant, and organic solvents in enhancing the sensitivity and loading of glucose oxidase (GOx) on polypyrrole film in a biosensor: A comparative study [J].

Safarnavadeh, Vahideh ;

Zare, Karim ;

Fakhari, Ali Reza .

BIOSENSORS & BIOELECTRONICS, 2013, 49 :159-163

[29]

Smyj R, 2013, PROF DRUG SUB EXCIP, V38, P463, DOI 10.1016/B978-0-12-407691-4.00011-3

[30] Assay of tramadol in urine by capillary electrophoresis using laser-induced native fluorescence detection [J].

Soetebeer, UB ;

Schierenberg, MO ;

Schulz, H ;

Grünefeld, G ;

Andresen, P ;

Blaschke, G .

JOURNAL OF CHROMATOGRAPHY B, 2000, 745 (02) :271-278

← 1 2 3 4 →