Implementation of the JACIE standards for a haematopoietic progenitor cell transplantation programme:: a cost analysis

The purpose of the present project was to analyse the costs incurred by the implementation of JACIE standards at a University Hospital with 1000 beds, performing some 40 autologous transplants per year. The cost analysis was performed on the basis of a prospective assessment of the time spent by all staff members involved with the implementation over a 14-month period of the quality management system (QMS) required by the JACIE standards. Two physicians worked on JACIE Section A (management = 82 h), one physician and two nurses for section Ba (clinical unit adults = 125.75 h), two physicians and three nurses for section Bp ( clinical unit paediatrics = 206 h), one physician, two nurses and one technician for section C ( progenitor cell collection facility = 105.75 h), and one physician and two technicians for section D ( progenitor cell processing facility = 426 h). The total time spent on the project amounted to 945.5 h with a total salary cost of is an element of150000. We concluded that implementation of the JACIE standards was accomplished within a 14-month period with a financial impact of approximately is an element of150000. The impact on quality parameters (eg clinical and laboratory end points, side effects) on HPC transplantation will be assessed in a second report after the first year of practical implementation.