Novel understanding of self-reactive T cells

被引：1

作者：

Andersen, Mads Hald ^{[1
]}

机构：

[1] Copenhagen Univ Hosp, Dept Hematol, Ctr Canc Immune Therapy CCIT, Herlev, Denmark

来源：

ONCOIMMUNOLOGY | 2016年 / 5卷 / 03期

关键词：

Anti-Tregs; CD8; IDO; PD-L1; self-reactive T cells; thymic selection;

D O I：

10.1080/2162402X.2015.1083672

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In a recent issue of Immunity, Mark Davis and colleagues describe that thymic selection does not eliminate but prunes self-reactive T cell clones. Self-reactive T cells are a natural part of the T-cell repertoire and may be important in the fight against pathogens in addition to being important immune regulators.

引用

页数：2

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