A novel method for the line-of-response and time-of-flight reconstruction in TOF-PET detectors based on a library of synchronized model signals

被引:100
作者
Moskal, P. [1 ]
Zon, N. [1 ]
Bednarski, T. [1 ]
Bialas, P. [1 ]
Czerwinski, E. [1 ]
Gajos, A. [1 ]
Kaminska, D. [1 ]
Kaplon, L. [1 ,2 ]
Kochanowski, A. [3 ]
Korcyl, G. [1 ]
Kowal, J. [1 ]
Kowalski, P. [4 ]
Kozik, T. [1 ]
Krzemien, W. [1 ]
Kubicz, E. [1 ]
Niedzwiecki, Sz [1 ]
Palka, M. [1 ]
Raczynski, L. [4 ]
Rudy, Z. [1 ]
Rundel, O. [1 ]
Salabura, P. [1 ]
Sharma, N. G. [1 ]
Silarski, M. [1 ]
Slomski, A. [1 ]
Smyrski, J. [1 ]
Strzelecki, A. [1 ]
Wieczorek, A. [1 ,2 ]
Wislicki, W. [4 ]
Zielinski, M. [1 ]
机构
[1] Jagiellonian Univ, Fac Phys Astron & Appl Comp Sci, PL-30348 Krakow, Poland
[2] Polish Acad Sci, Inst Met & Mat Sci, PL-30059 Krakow, Poland
[3] Jagiellonian Univ, Fac Chem, PL-30060 Krakow, Poland
[4] Natl Ctr Nucl Res, Swierk Comp Ctr, PL-05400 Otwock, Poland
关键词
Scintillator detectors; Positron Emission Tomography; Time-of-flight; J-PET; SINGLE MODULE; STRIP-PET; DESIGN; DEPTH; SCINTILLATORS; PERFORMANCE; CALIBRATION; SCATTERING;
D O I
10.1016/j.nima.2014.12.005
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
A novel method of hit time and hit position reconstruction in scintillator detectors is described. The method is based on comparison of detector signals with results stored in a library of synchronized model signals registered for a set of well-defined positions of scintillation points. The hit position is reconstructed as the one corresponding to the signal from the library which is most similar to the measurement signal. The time of the interaction is determined as a relative time between the measured signal and the most similar one in the library. A degree of similarity of measured and model signals is defined as the distance between points representing the measurement- and model-signal in the multidimensional measurement space. Novelty of the method lies also in the proposed way of synchronization of model signals enabling direct determination of the difference between time-of-flights (TOF) of annihilation quanta from the annihilation point to the detectors. The introduced method was validated using experimental data obtained by means of the double strip prototype of the J-PET detector and Na-22 sodium isotope as a source of annihilation gamma quanta. The detector was built out from plastic scintillator strips with dimensions of 5 mm x 19 mm x 300 mm, optically connected at both sides to photomultipliers, from which signals were sampled by means of the Serial Data Analyzer. Using the introduced method, the spatial and TOP resolution of about 1.3 cm (sigma) and 125 ps (sigma) were established, respectively. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:54 / 62
页数:9
相关论文
共 44 条
[1]  
[Anonymous], 2014, RADIOTHERAPHY ONCOLO
[2]   Calibration of photomultipliers gain used in the J-PET detector [J].
Bednarski, Tomasz ;
Czerwinski, Eryk ;
Moskal, Pawel ;
Bialas, Piotr ;
Giergiel, Krzysztof ;
Kaplon, Lukasz ;
Kochanowski, Andrzej ;
Korcyl, Grzegorz ;
Kowal, Jakub ;
Kowalski, Pawel ;
Kozik, Tomasz ;
Krzemien, Wojciech ;
Molenda, Marcin ;
Moskal, Ines ;
Niedzwiecki, Szymon ;
Palka, Marek ;
Pawlik, Monika ;
Raczynski, Lech ;
Rudy, Zbigniew ;
Salabura, Piotr ;
Sharma, Neha Gupta ;
Silarski, Michal ;
Slomski, Artur ;
Smyrski, Jerzy ;
Strzelecki, Adam ;
Szymanski, Konrad Jan ;
Wislicki, Wojciech ;
Witkowski, Piotr ;
Zielinski, Marcin ;
Zon, Natalia .
BIO-ALGORITHMS AND MED-SYSTEMS, 2014, 10 (01) :13-17
[3]  
Belli G., 2006, Journal of Physics: Conference Series, V41, P555, DOI 10.1088/1742-6596/41/1/068
[4]   Physical Performance of the new hybrid PET/CT Discovery-690 [J].
Bettinardi, V. ;
Presotto, L. ;
Rapisarda, E. ;
Picchio, M. ;
Gianolli, L. ;
Gilardi, M. C. .
MEDICAL PHYSICS, 2011, 38 (10) :5394-5411
[5]   Efficiency of RPC detectors for whole-body human TOF-PET [J].
Blanco, A. ;
Couceiro, M. ;
Crespo, P. ;
Ferreira, N. C. ;
Marques, R. Ferreira ;
Fonte, P. ;
Lopes, L. ;
Neves, J. A. .
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2009, 602 (03) :780-783
[6]   State of the art and challenges of time-of-flight PET [J].
Conti, Maurizio .
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 2009, 25 (01) :1-11
[7]   Comparison of Fast Scintillators With TOF PET Potential [J].
Conti, Maurizio ;
Eriksson, Lars ;
Rothfuss, Harold ;
Melcher, Charles L. .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2009, 56 (03) :926-933
[8]  
Crosetto D.B., 2003, INT J MED TECHNOLOGY, V1
[9]   Design of field-cycled magnetic resonance systems for small animal imaging [J].
Gilbert, K. M. ;
Handler, W. B. ;
Scholl, T. J. ;
Odegaard, J. W. ;
Chronik, B. A. .
PHYSICS IN MEDICINE AND BIOLOGY, 2006, 51 (11) :2825-2841
[10]   From PET detectors to PET scanners [J].
Humm, JL ;
Rosenfeld, A ;
Del Guerra, A .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2003, 30 (11) :1574-1597