Safety and efficacy of paramedic treatment of regular supraventricular tachycardia: a randomised controlled trial

被引:9
|
作者
Honarbakhsh, S. [1 ]
Baker, V. [1 ]
Kirkby, C. [1 ]
Patel, K. [1 ]
Robinson, G. [1 ]
Antoniou, S. [1 ]
Richmond, L. [1 ]
Ullah, W. [1 ]
Hunter, R. J. [1 ]
Finlay, M. [1 ]
Earley, M. J. [1 ]
Whitbread, M. [2 ]
Schilling, R. J. [1 ]
机构
[1] Barts Hlth NHS Trust, St Bartholomews Hosp, Barts Heart Ctr, Cardiovasc Biomed Res Unit, London, England
[2] London Ambulance Serv, London, England
关键词
PREHOSPITAL MANAGEMENT; INTRAVENOUS ADENOSINE;
D O I
10.1136/heartjnl-2016-309968
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction Supraventricular tachycardias (SVTs) are a common cause of acute hospital presentations. Adenosine is an effective treatment. To date, no studies have directly compared paramedic-with hospital-delivered treatment of acute SVT with adenosine. Method Randomised controlled trial comparing the treatment of SVT and discharge by paramedics with conventional emergency department (ED)-based care. Patients were excluded if they had structural heart disease or contraindication to adenosine. Discharge time, follow-up management, costs and patient satisfaction were compared. Results Eighty-six patients were enrolled: 44 were randomised to paramedic-delivered adenosine (PARA) and 42 to conventional care (ED). Of the 37 patients in the PARA group given adenosine, the tachycardia was successfully terminated in 81%. There was a 98% correlation between the paramedics' ECG diagnosis and that of two electrophysiologists. No patients had any documented adverse events in either group. The discharge time was lower in the PARA group than in the ED group (125 min (range 55-9513) vs 222 min (range 7226 153); p=0.01), and this treatment strategy was more cost-effective ( pound 282 vs pound 423; p=0.01). The majority of patients preferred this management approach. Being treated and discharged by paramedics did not result in the patients being less likely to receive ongoing management of their arrhythmia and cardiology follow-up. Conclusions Patients with SVT can effectively and safely be treated with adenosine delivered by trained paramedics. Implementation of paramedic-delivered acute SVT care has the potential to reduce healthcare costs without compromising patient care.
引用
收藏
页码:1413 / 1418
页数:6
相关论文
共 50 条
  • [1] SAFETY AND EFFICACY OF PARAMEDIC TREATMENT OF REGULAR SUPRAVEENTRICULAR TACHYCARDIA
    Baker, A.
    Whitbread, M.
    Richmond, L.
    Kirkby, C.
    Robinson, G.
    Antoniou, S.
    Schilling, R.
    HEART, 2013, 99 : A46 - A46
  • [2] EFFICACY AND SAFETY OF ADENOSINE IN THE TREATMENT OF SUPRAVENTRICULAR TACHYCARDIA IN INFANTS AND CHILDREN
    TILL, J
    SHINEBOURNE, EA
    RIGBY, ML
    CLARKE, B
    WARD, DE
    ROWLAND, E
    BRITISH HEART JOURNAL, 1989, 62 (03): : 204 - 211
  • [3] Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trial
    Nicholson, KG
    Aoki, FY
    Osterhaus, ADME
    Trottier, S
    Carewicz, O
    Mercier, CH
    Rode, A
    Kinnersley, N
    Ward, P
    LANCET, 2000, 355 (9218): : 1845 - 1850
  • [4] ANTIARRHYTHMIC EFFICACY AND SAFETY OF ESMOLOL IN SUPRAVENTRICULAR TACHYCARDIA
    MACCOSBE, PE
    GRAY, R
    SAWIN, H
    LESTER, R
    TSCHIDA, V
    HOFF, J
    BREHM, J
    ALLIN, D
    TURLAPATY, P
    LADDU, AR
    DRUG INTELLIGENCE & CLINICAL PHARMACY, 1985, 19 (06): : 446 - 446
  • [5] EFFICACY AND SAFETY OF INTRAVENOUS NADOLOL FOR SUPRAVENTRICULAR TACHYCARDIA
    OLUKOTUN, AY
    KLEIN, GJ
    AMERICAN JOURNAL OF CARDIOLOGY, 1987, 60 (06): : D59 - D62
  • [6] Efficacy and safety of adenosine in diagnosis and treatment of regular tachycardia in the elderly
    Camaiti, A
    Del Rosso, A
    Morettini, A
    Nozzoli, C
    Grifoni, S
    Berni, G
    CORONARY ARTERY DISEASE, 1998, 9 (09) : 591 - 596
  • [7] EFFICACY OF INTRAVENOUS SOTALOL IN THE TREATMENT OF SUPRAVENTRICULAR TACHYCARDIA
    DENIS, J
    BRUNEL, P
    MOISAN, A
    ANNALES DE CARDIOLOGIE ET D ANGEIOLOGIE, 1988, 37 (07): : 387 - 391
  • [8] Efficacy and Safety of Diethylcarbamazine in Treatment of Allergic Rhinitis: A Double Blind Randomised Controlled Trial
    Mohana Karthikeyan, S.
    Nikisha, G. N.
    INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY, 2022, 74 (SUPPL 2) : 1169 - 1177
  • [9] Efficacy and Safety of Diethylcarbamazine in Treatment of Allergic Rhinitis: A Double Blind Randomised Controlled Trial
    S. Mohana Karthikeyan
    G. N. Nikisha
    Indian Journal of Otolaryngology and Head & Neck Surgery, 2022, 74 : 1169 - 1177
  • [10] THE EFFICACY AND SAFETY OF GENTAMICIN FOR THE TREATMENT OF GENITAL, PHARYNGEAL AND RECTAL GONORRHOEA: A RANDOMISED CONTROLLED TRIAL
    Ross, Jonathan D. C.
    Harding, Jan
    Duley, Lelia
    Montgomery, Alan A.
    Hepburn, Trish
    Tan, Wei
    Brittain, Clare
    Meakin, Garry
    Thandi, Sukhy
    Lawrence, Tessa
    Cole, Michelle
    Wilson, Janet
    White, John
    Jackson, Louise
    Roberts, Tracy
    SEXUALLY TRANSMITTED INFECTIONS, 2017, 93 : A42 - A43