In vivo confocal microscopy in a patient with keratopigmentation (corneal tattooing)

Purpose: To report in vivo corneal confocal microscopic findings in a patient with keratopigmentation (corneal tattooing). Patients and Methods: A 64-year-old woman who received keratopigmentation for bilateral corneal opacity 53 years ago was examined by confocal microscope. Results: By confocal microscopy, scattered highly reflective particles in a geographic pattern were observed in the superficial stroma near Bowman layer. In addition, clusters of highly reflective,granules were in the mid- to superficial stroma. Conclusions: In vivo confocal microscopy can be used for monitoring keratopigmentation. The findings may serve to distinguish keratopigmentations from other pigmented corneal lesions.