Recent Progress in the Functionalization of Benzo-γ-Pyrones via Transition-Metal Catalyzed Cross-Coupling Reactions

被引：2

作者：

Ming, Xianjun ^{[1
]}

Yang, Kan ^{[1
]}

Gao, Biao ^{[1
]}

Gu, Qinlan ^{[2
]}

Wang, Jinxin ^{[1
]}

机构：

[1] China Pharmaceut Univ, Key Lab Drug Design & Optimizat Jiangsu Prov, Nanjing 210009, Jiangsu, Peoples R China

[2] China Pharmaceut Univ, Higher Vocat & Tech Coll, Nanjing 210009, Jiangsu, Peoples R China

来源：

MINI-REVIEWS IN ORGANIC CHEMISTRY | 2016年 / 13卷 / 01期

关键词：

Benzo-gamma-pyrone; carbon-carbon bond; cross-coupling; natural products; palladium-catalyzed; vinyl halides/triflates; BIOLOGICAL EVALUATION; SUZUKI-MIYAURA; CHROMONE DERIVATIVES; C-C; POTENT; INHIBITORS; DESIGN; FLAVONES; ANALOGS; GLAZIOVIANIN;

D O I：

10.2174/1570193X13666160225000421

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzo-gamma-pyrone derivatives have attracted increasing attentions due to their significant biological activities. Structural modifications based on benzo-gamma-pyrone scaffold are being carried out in several ways in order to anticipate enhanced biological activities. This review mainly covers recent studies on the functionalization of benzo-gamma-pyrone scaffold by using different transition-metalcatalyzed cross-coupling reactions, which provides an in depth view of diversity-oriented synthesis of benzo-gamma-pyrone derivatives.

引用

页码：31 / 48

页数：18

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