Surface proteins of Streptococcus agalactiae and horizontal gene transfer

被引:15
作者
Bröker, G [1 ]
Spellerberg, B [1 ]
机构
[1] Univ Ulm, Dept Med Microbiol & Hyg, D-89081 Ulm, Germany
关键词
surface protein; recombination; streptococcus; mobile genetic element;
D O I
10.1016/j.ijmm.2004.06.018
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Streptococcus agalactiae is responsible for serious infectious diseases in neonates, immuno-compromised adult patients and causes bovine mastitis in animal hosts. Genome sequencing projects revealed strong indications for horizontal gene transfer events leading to virulence acquisition and genetic diversity in this species. Bacterial surface proteins establish the first contact with host tissues and represent interesting targets for the exchange of virulence properties among different streptococci. This review will focus on horizontal gene transfer events in characterized S. agalactiae surface proteins, mobile genetic elements adjacent to the corresponding genes and will discuss potential mechanisms of transfer. (C) 2004 Elsevier GmbH. All rights reserved.
引用
收藏
页码:169 / 175
页数:7
相关论文
共 41 条
[1]   A role for C5 and C5a-ase in the acute neutrophil response to group B streptococcal infections [J].
Bohnsack, JF ;
Widjaja, K ;
Ghazizadeh, S ;
Rubens, CE ;
Hillyard, DR ;
Parker, CJ ;
Albertine, KH ;
Hill, HR .
JOURNAL OF INFECTIOUS DISEASES, 1997, 175 (04) :847-855
[2]   Long-range mapping of the Streptococcus agalactiae phylogenetic lineage restriction digest pattern type III-3 reveals clustering of virulence genes [J].
Bohnsack, JF ;
Whiting, AA ;
Bradford, RD ;
Van Frank, BK ;
Takahashi, S ;
Adderson, EE .
INFECTION AND IMMUNITY, 2002, 70 (01) :134-139
[3]   The alpha C protein mediates internalization of group B Streptococcus within human cervical epithelial cells [J].
Bolduc, GR ;
Baron, MJ ;
Gravekamp, C ;
Lachenauer, CS ;
Madoff, LC .
CELLULAR MICROBIOLOGY, 2002, 4 (11) :751-758
[4]   The group B streptococcal C5a peptidase is both a specific protease and an invasin [J].
Cheng, Q ;
Stafslien, D ;
Purushothaman, SS ;
Cleary, P .
INFECTION AND IMMUNITY, 2002, 70 (05) :2408-2413
[5]   Conservation of the C5a peptidase genes in group A and B streptococci [J].
Chmouryguina, I ;
Suvorov, A ;
Ferrieri, P ;
Cleary, PP .
INFECTION AND IMMUNITY, 1996, 64 (07) :2387-2390
[6]   Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases [J].
Dintilhac, A ;
Alloing, G ;
Granadel, C ;
Claverys, JP .
MOLECULAR MICROBIOLOGY, 1997, 25 (04) :727-739
[7]   Genetic heterogeneity of the pathogenic potentials of human and bovine group B streptococci [J].
Dmitriev, A ;
Shakleina, E ;
Tkáciková, L ;
Mikula, I ;
Totolian, A .
FOLIA MICROBIOLOGICA, 2002, 47 (03) :291-295
[8]   Involvement of Lsp, a member of the LraI-lipoprotein family in Streptococcus pyogenes, in eukaryotic cell adhesion and internalization [J].
Elsner, A ;
Kreikemeyer, B ;
Braun-Kiewnick, A ;
Spellerberg, B ;
Buttaro, BA ;
Podbielski, A .
INFECTION AND IMMUNITY, 2002, 70 (09) :4859-4869
[9]   What happened to the streptococci: Overview of taxonomic and nomenclature changes [J].
Facklam, R .
CLINICAL MICROBIOLOGY REVIEWS, 2002, 15 (04) :613-+
[10]   Horizontal gene transfer and host specificity of beta-haemolytic streptococci:: the role of a putative composite transposon containing scpB and lmb [J].
Franken, C ;
Haase, G ;
Brandt, C ;
Weber-Heynemann, J ;
Martin, S ;
Lämmler, C ;
Podbielski, A ;
Lütticken, R ;
Spellerberg, B .
MOLECULAR MICROBIOLOGY, 2001, 41 (04) :925-935