A New Approch for Catalyst Optimization: Host/Guest Complexes of Chiral Bisphosphine Bearing Imidazolidinone and Their Application in Rh-Catalyzed Asymmetric Hydrogenation

被引：1
作者：
Park, Jung Hwan [1 ]
Shin, Hyunik [2 ]
Park, Doo Han [3 ]
Lee, Sang-gi [1 ]
机构：
[1] Ewha Womans Univ, Dept Chem & Nano Sci BK21, Seoul 120750, South Korea
[2] LG Life Sci Ltd, Res & Dev, Chem Dev Div, Taejon 305380, South Korea
[3] Sahmyook Univ, Dept Chem, Seoul 139742, South Korea
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2010年 / 31卷 / 03期
基金：
新加坡国家研究基金会;
关键词：
Chiral catalyst; Catalyst optimization; Host/guest; MOLECULAR RECOGNITION; LIGANDS;
D O I：
10.5012/bkcs.2010.31.03.635
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
As a new strategy for the optimization of a chiral catalyst, the catalytic activity of the host-guest complexes of chiral bisphosphine bearing imidazolidinone was investigated in Rh-catalyzed asymmetric hydrogenation of enamide. Marginal enhancement in enantioselectivity was observed and the nature of interaction between host-fittest was experimentally elucidated.
引用
收藏
页码：635 / 638
页数：4
相关论文
共 16 条
  • [1] Allinger N.L., 1980, QCPE, V12, P395
  • [2] [Anonymous], MOL MECH
  • [3] BELL DA, 1996, COMPREHENSIVE SUPRAM, V2, P439
  • [4] MOLECULAR RECOGNITION IN AQUEOUS-MEDIA - CONFORMATIONALLY RESTRICTED WATER-SOLUBLE CYCLOPHANES DERIVED FROM 6H,12H-5,11-METHANODIBENZO[B,F][1,5]DIAZOCINE
    COWART, MD
    SUCHOLEIKI, I
    BUKOWNIK, RR
    WILCOX, CS
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (18) : 6204 - 6210
  • [5] Determination of association constants (Ka) from solution NMR data
    Fielding, L
    [J]. TETRAHEDRON, 2000, 56 (34) : 6151 - 6170
  • [6] Hedge Vidyadhar, 1993, Journal of the American Chemical Society, V115, P872
  • [7] Lee SG, 2002, ANGEW CHEM INT EDIT, V41, P847, DOI 10.1002/1521-3773(20020301)41:5<847::AID-ANIE847>3.0.CO
  • [8] 2-F
  • [9] Molecular recognition of carbohydrates with acyclic pyridine-based receptors
    Mazik, M
    Radunz, W
    Boese, R
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2004, 69 (22) : 7448 - 7462
  • [10] MACROMODEL - AN INTEGRATED SOFTWARE SYSTEM FOR MODELING ORGANIC AND BIOORGANIC MOLECULES USING MOLECULAR MECHANICS
    MOHAMADI, F
    RICHARDS, NGJ
    GUIDA, WC
    LISKAMP, R
    LIPTON, M
    CAUFIELD, C
    CHANG, G
    HENDRICKSON, T
    STILL, WC
    [J]. JOURNAL OF COMPUTATIONAL CHEMISTRY, 1990, 11 (04) : 440 - 467
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