Neo-clerodane diterpenoids from Croton schiedeanus

被引:28
|
作者
Puebla, P [1 ]
López, JL
Guerrero, M
Carrón, R
Martín, ML
San Román, L
San Feliciano, A
机构
[1] Fac Farm, Dept Quim Farmaceut, E-37007 Salamanca, Spain
[2] Univ Nacl Colombia, Fac Ciencias, Dept Farm, AA-11430 Bogota, Colombia
[3] Fac Farm, Dept Fisiol & Farmacol, E-37007 Salamanca, Spain
关键词
Croton schiedeanus; euphorbiaceae; neo-clerodane diterpenoids; 5; beta-hydroxy-cis-dehydrocrotonin; (12R)-12-hydroxycascarillone;
D O I
10.1016/S0031-9422(02)00516-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two new neo-clerodane type furano diterpenoids were isolated from the aerial part of Croton schiedeanus, besides the clerodane diterpenes cis- and trans-dehydrocrotonin, previously isolated from other species of Croton. Structural elucidation was achieved on basis of extensive NMR experiments, including X-ray diffraction analysis and molecular mechanics calculations. The previously known flavonoids ayanin and quercetin-3,7-dimethyl ether were also obtained from the extract of this plant. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:551 / 555
页数:5
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