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Neo-clerodane diterpenoids from Croton schiedeanus
被引:28
|作者:
Puebla, P
[1
]
López, JL
Guerrero, M
Carrón, R
Martín, ML
San Román, L
San Feliciano, A
机构:
[1] Fac Farm, Dept Quim Farmaceut, E-37007 Salamanca, Spain
[2] Univ Nacl Colombia, Fac Ciencias, Dept Farm, AA-11430 Bogota, Colombia
[3] Fac Farm, Dept Fisiol & Farmacol, E-37007 Salamanca, Spain
关键词:
Croton schiedeanus;
euphorbiaceae;
neo-clerodane diterpenoids;
5;
beta-hydroxy-cis-dehydrocrotonin;
(12R)-12-hydroxycascarillone;
D O I:
10.1016/S0031-9422(02)00516-2
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Two new neo-clerodane type furano diterpenoids were isolated from the aerial part of Croton schiedeanus, besides the clerodane diterpenes cis- and trans-dehydrocrotonin, previously isolated from other species of Croton. Structural elucidation was achieved on basis of extensive NMR experiments, including X-ray diffraction analysis and molecular mechanics calculations. The previously known flavonoids ayanin and quercetin-3,7-dimethyl ether were also obtained from the extract of this plant. (C) 2002 Elsevier Science Ltd. All rights reserved.
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页码:551 / 555
页数:5
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