Preparation of hexahydrobenzo[f]isoquinolines using a vinylogous Pictet-Spengler cyclization

被引：19

作者：

Cesati, RR ^{[1
]}

Katzenellenbogen, JA ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 23期

关键词：

D O I：

10.1021/ol006533u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A vinylogous Pictet-Spengler cyclization has been carried out using activated aldehydes, ketones, and alkynes to prepare a variety of substituted hexahydrobenzo[f]isoquinolines. A unique set of conditions was utilized to effect efficient cyclization with acid sensitive electrophiles.

引用

页码：3635 / 3638

页数：4

共 39 条

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