A novel and efficient Lewis acid catalysed preparation of pyrimidines:: Microwave-promoted reaction of urea and β-formyl enamides

被引：44

作者：

Barthakur, Madan G. ^{[1
]}

Borthakur, Moyurima ^{[1
]}

Devi, Prarthana ^{[1
]}

Saikia, Chandan J. ^{[1
]}

Saikia, Anil ^{[1
]}

Bora, Utpal ^{[1
]}

Chetia, Apurba ^{[1
]}

Boruah, Romesh C. ^{[1
]}

机构：

[1] Reg Res Lab, Div Med Chem, Jorhat 785006, Assam, India

来源：

SYNLETT | 2007年 / 02期

关键词：

beta-formyl enamide; urea; microwave; pyrimidine;

D O I：

10.1055/s-2007-968018

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient synthesis of pyrimidine from beta-formyl enamide is described. The key step involves samarium chloride catalysed cyclisation of beta-formyl enamides using urea as source of ammonia under microwave irradiation.

引用

页码：223 / 226

页数：4

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