In vitro corrosion and cytotoxicity on microcrystalline, nanocrystalline and amorphous NiTi alloy fabricated by high pressure torsion

被引：42

作者：

Nie, F. L. ^{[1
,2
]}

Zheng, Y. F. ^{[1
,2
,3
]}

Cheng, Y. ^{[3
]}

Wei, S. C. ^{[3
,4
]}

Valiev, R. Z. ^{[5
]}

机构：

[1] Peking Univ, Coll Engn, Dept Adv Mat & Nanotechnol, Beijing 100871, Peoples R China

[2] Peking Univ, Coll Engn, State Key Lab Turbulence & Complex Syst, Beijing 100871, Peoples R China

[3] Peking Univ, Ctr Biomed Mat & Tissue Engn, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China

[4] Peking Univ, Sch Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China

[5] Ufa State Aviat Tech Univ, Inst Phys Adv Mat, Ufa, Russia

来源：

MATERIALS LETTERS | 2010年 / 64卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Ni50.2Ti49.8; alloy; Nanocrystalline; Amorphous; Metals and alloys; Corrosion and ion release; Cytotoxicity; BIOCOMPATIBILITY;

D O I：

10.1016/j.matlet.2010.01.081

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Bulk nanocrystalline and amorphous Ni50.2Ti49.8 alloy samples were successfully prepared from commercial microcrystalline Ni50.2Ti49.8 alloy discs by high pressure torsion (HPT) technique. Then their corrosion resistance, surface wettability and cytotoxicity were further studied from the viewpoint of biomaterials. In both Hank's solution and artificial saliva, bulk nanocrystalline and amorphous Ni50.2Ti49.8 alloys showed significantly higher pitting corrosion potentials than that of microcrystalline Ni50.2Ti49.8 alloy. Meanwhile, the amount of Ni ion release after immersion in Hank's solution was minor, far below the threatening threshold of daily diet. Murine fibroblast and osteoblast cell lines were indirectly co-cultured with experimental sample extracts, indicating no cytotoxicity. Amongst all samples, the nanocrystalline Ni50.2Ti49.8 shows promising as best biomaterial candidate for its good combination of mechanical property, corrosion resistance and cytocompatibility. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：983 / 986

页数：4

共 10 条

[1] TOXICITY AND CARCINOGENICITY OF NICKEL COMPOUNDS [J].