Rhodococcus equi hyperimmune plasma decreases pneumonia severity after a randomised experimental challenge of neonatal foals

被引：25

作者：

Sanz, M. G. ^{[1
]}

Loynachan, A. ^{[2
]}

Horohov, D. W. ^{[1
]}

机构：

[1] Univ Kentucky, Maxwell H Gluck Equine Res Ctr, Lexington, KY 40546 USA

[2] Univ Kentucky, Dept Vet Sci, Vet Diagnost Lab, Lexington, KY 40546 USA

来源：

VETERINARY RECORD | 2016年 / 178卷 / 11期

关键词：

SUBCLINICAL PULMONARY ABSCESSES; VIRULENCE; RESPONSES; IGG; PREVENTION; PROTECTION; DIAGNOSIS; ANTIBODY; AGE;

D O I：

10.1136/vr.103095

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Since a vaccine is not available against Rhodococcus equi, R equi-specific hyperimmune plasma (HIP) is commonly used, although its efficacy remains controversial. The objective of this study was to evaluate the ability of a commercially available HIP to prevent clinical rhodococcal pneumonia in neonatal foals after experimental challenge.

引用

页数：7

共 45 条

[31]

Perkins Gillian A, 2002, Vet Ther, V3, P334

[32] Nitrogenous metabolism in thoroughbred and Arabian foals from birth to five months of age [J].

Piccione, G. ;

Costa, A. ;

Fazio, F. ;

Grasso, F. ;

Caola, G. .

ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA, 2006, 58 (04) :525-529

[33] Diagnostic contribution of thoracic ultrasonography in 17 foals with Rhodococcus equi pneumonia [J].

Ramirez, S ;

Lester, GD ;

Roberts, GR .

VETERINARY RADIOLOGY & ULTRASOUND, 2004, 45 (02) :172-176

[34] The effect of bacterial dose and foal age at challenge on Rhodococcus equi infection [J].

Sanz, M. ;

Loynachan, A. ;

Sun, L. ;

Oliveira, A. ;

Breheny, P. ;

Horohov, D. W. .

VETERINARY MICROBIOLOGY, 2013, 167 (3-4) :623-631

[35]

SANZ M, 2014, EQUINE VET J, V48, P103

[36] Administration of commercial Rhodococcus equi specific hyperimmune plasma results in variable amounts of IgG against pathogenic bacteria in foals [J].

Sanz, M. G. ;

Oliveira, A. F. ;

Page, A. ;

Horohov, D. W. .

VETERINARY RECORD, 2014, 175 (19) :485

[37] Comparison of nucleic acid amplification, serology, and microbiologic culture for diagnosis of Rhodococcus equi pneumonia in foals [J].

Sellon, DC ;

Besser, TE ;

Vivrette, SL ;

McConnico, RS .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (04) :1289-1293

[38] Immunoglobulin isotypes in sera and nasal mucosal secretions and their neonatal transfer and distribution in horses [J].

Sheoran, AS ;

Timoney, JF ;

Holmes, MA ;

Karzenski, SS ;

Crisman, MV .

AMERICAN JOURNAL OF VETERINARY RESEARCH, 2000, 61 (09) :1099-1105

[39]

SOMA LR, 1988, AM J VET RES, V49, P1894

[40]

TAFAZZOLI M, 2006, UHOD-ULUSLAR HEMATOL, V16, P71

← 1 2 3 4 5 →