Current Concepts: Management of Varices and Variceal Hemorrhage in Cirrhosis.

被引:643
作者
Garcia-Tsao, Guadalupe [1 ]
Bosch, Jaime [2 ]
机构
[1] Yale Univ, Sch Med, Sect Digest Dis, New Haven, CT 06520 USA
[2] Univ Barcelona, Hosp Clin, Hepat Hemodynam Lab, Liver Unit, Barcelona, Spain
关键词
PORTAL HYPERTENSIVE GASTROPATHY; RANDOMIZED CONTROLLED-TRIAL; VENOUS-PRESSURE GRADIENT; INTRAHEPATIC PORTOSYSTEMIC SHUNT; SMALL ESOPHAGEAL-VARICES; NATURAL-HISTORY; PHARMACOLOGICAL-TREATMENT; CYANOACRYLATE INJECTION; ENDOSCOPIC TREATMENT; BAND LIGATION;
D O I
10.1056/NEJMra0901512
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gastroesophageal varices are present at diagnosis in almost half of patients with cirrhosis, and variceal hemorrhage continues to be a lethal complication of cirrhosis. This review explains the three main challenges in clinical management: primary prophylaxis to prevent a first episode of hemorrhage, the treatment of acute bleeding episodes, and secondary prophylaxis to prevent recurrence of variceal hemorrhage. Copyright © 2010 Massachusetts Medical Society.
引用
收藏
页码:823 / 832
页数:10
相关论文
共 50 条
  • [1] Prevention and management of Gastroesophageal varices and variceal Hemorrhage in cirrhosis
    Garcia-Tsao, Guadalupe
    Sanyal, Arun J.
    Grace, Norman D.
    Carey, William
    HEPATOLOGY, 2007, 46 (03) : 922 - 938
  • [2] Management of varices and variceal hemorrhage in liver cirrhosis: a recent update
    Diaz-Soto, Maria P.
    Garcia-Tsao, Guadalupe
    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2022, 15
  • [3] Challenges in the Management of Esophagogastric Varices and Variceal Hemorrhage in Cirrhosis - A Narrative Review
    Gralnek, Ian M.
    Garcia-Pagan, Juan Carlos
    Gea, Virginia Hernandez
    AMERICAN JOURNAL OF MEDICINE, 2024, 137 (03) : 210 - 217
  • [4] Varices and Variceal Hemorrhage in Cirrhosis: A New View of an Old Problem
    Garcia-Tsao, Guadalupe
    Bosch, Jaime
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2015, 13 (12) : 2109 - 2117
  • [5] Management of varices in patients with cirrhosis
    O'Brien, Julia
    Triantos, Christos
    Burroughs, Andrew K.
    NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2013, 10 (07) : 402 - 412
  • [6] Management of varices in cirrhosis
    Thalheimer, Ulrich
    Triantos, Christos
    Goulis, John
    Burroughs, Andrew K.
    EXPERT OPINION ON PHARMACOTHERAPY, 2011, 12 (05) : 721 - 735
  • [7] The role of endoscopy in the management of variceal hemorrhage
    Hwang, Joo Ha
    Shergill, Amandeep K.
    Acosta, Ruben D.
    Chandrasekhara, Vinay
    Chathadi, Krishnavel V.
    Decker, G. Anton
    Early, Dayna S.
    Evans, John A.
    Fanelli, Robert D.
    Fisher, Deborah A.
    Foley, Kimberly Q.
    Fonkalsrud, Lisa
    Jue, Terry
    Khashab, Mouen A.
    Lightdale, Jenifer R.
    Muthusamy, V. Raman
    Pasha, Shabana F.
    Saltzman, John R.
    Sharaf, Ravi
    Cash, Brooks D.
    GASTROINTESTINAL ENDOSCOPY, 2014, 80 (02) : 221 - 227
  • [8] Nomogram for predicting the risk of gastroesophageal varices after primary endoscopic prophylaxis for variceal hemorrhage in patients with cirrhosis
    Zhang, Shuo
    Song, Weiping
    Chang, Yizhong
    Wang, Shenglan
    Yang, Li
    Yang, Changqing
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2021, 33 : E131 - E139
  • [9] Evaluation and Management of Esophageal and Gastric Varices in Patients with Cirrhosis
    Jakab, Sofia Simona
    Garcia-Tsao, Guadalupe
    CLINICS IN LIVER DISEASE, 2020, 24 (03) : 335 - +
  • [10] MANAGEMENT OF ACUTE ESOPHAGEAL VARICEAL HEMORRHAGE
    Lo, Gin-Ho
    KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2010, 26 (02) : 55 - 67