New stable reagents for the nucleophilic trifluoromethylation.: 1.: Trifluoromethylation of carbonyl compounds with N-formylmorpholine derivatives

被引：105

作者：

Billard, T ^{[1
]}

Bruns, S ^{[1
]}

Langlois, BR ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, UMR 5622, SERCOF, F-69622 Villeurbanne, France

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 14期

关键词：

D O I：

10.1021/ol005987o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new stable equivalent of the trifluoromethyl anion has been synthesized from fluoroform, It reacts with nonenolizable carbonyl compounds such as the Ruppert's reagent.

引用

页码：2101 / 2103

页数：3

共 15 条

[1]

Banks R.E., 1994, ORGANOFLUORINE CHEM

[2]

Filler R., 1993, ORGANOFLUORINE COMPO

[3] Fluoroform:: An efficient precursor for the trifluoromethylation of aldehydes [J].

Folléas, B ;

Marek, I ;

Normant, JF ;

Saint Jalmes, L .

TETRAHEDRON LETTERS, 1998, 39 (19) :2973-2976

[4] Fluoroform:: an efficient precursor for the trifluoromethylation of aldehydes [J].

Folléas, B ;

Marek, I ;

Normant, JF ;

Saint-Jalmes, L .

TETRAHEDRON, 2000, 56 (02) :275-283

[5]

Gross U., 1999, ORGANOFLUORINE COM A, VE10a, P18

[6]

HUDLICKY M, 1995, ACS MONOGRAPH, V187

[7]

LARGE S, IN PRESS J ORG CHEM

[8]

Maggiarosa N, 1999, ANGEW CHEM INT EDIT, V38, P2252, DOI 10.1002/(SICI)1521-3773(19990802)38:15<2252::AID-ANIE2252>3.0.CO

[9]

2-Z

[10] TRIFLUOROMETHYLATIONS AND RELATED REACTIONS IN ORGANIC-CHEMISTRY [J].

MCCLINTON, MA ;

MCCLINTON, DA .

TETRAHEDRON, 1992, 48 (32) :6555-6666

← 1 2 →