Reactivity of a wollastonite-tricalcium phosphate Bioeutectic® ceramic in human parotid saliva

被引:116
作者
De Aza, PN
Luklinska, ZB
Anseau, MR
Hector, M
Guitián, F
De Aza, S
机构
[1] CSIC, Inst Ceram & Vidrio, Madrid 28500, Spain
[2] Univ Miguel Hernandez, Dept Ciencia & Tecnol Mat, Alicante 03202, Spain
[3] Queen Mary Univ London, Dept Mat, IRC Biomed Mat, London E1 4NS, England
[4] Queen Mary Univ London, St Bartholomews Hosp & Royal London Sch Med & Den, Dept Biomat Relat Dent, London E1 4NS, England
[5] Univ London, St Bartholomews & Royal London Sch Med & Dent, Dept Paediat Dent, London E1 2AD, England
[6] Univ Santiago, Inst Ceram, Santiago De Compostela, Spain
关键词
Bioeutectic (R); wollastonite; alpha-tricalcium phosphate; bioactivity; simulated body fluid; human parotid saliva;
D O I
10.1016/S0142-9612(00)00058-2
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In a previous study, a new ceramic material (Bioeutectic(R)), prepared by slow solidification through the eutectic temperature region of the wollastonite-tricalcium phosphate system, was found to be reactive in a simulated body fluid. In the present study, the reactivity of the Bioeutectic(R) was assessed in human parotid saliva. Samples of the material were soaked for one month in human parotid saliva at 37 degrees C. The experiments showed the formation of two separate zones of carbonate-hydroxyapatite-like phase on the periphery of the samples. The first zone was formed by reaction of the bioeutectic with the saliva and progressed inside the material. The other zone developed on the surface of the bioeutectic by precipitation from the media. The mechanism of carbonate-hydroxyapatite-like phase formation in human parotid saliva appeared to be similar to that of apatite-like phase found in a simulated body fluid. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1735 / 1741
页数:7
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